BACKGROUND Maternal diabetes affects the developing fetal cardiovascular system. Newborn offspring of diabetic mothers can have a transient cardiomyopathy. We hypothesized that cardiomyopathic remodeling is associated with activation of the mitogen activated protein kinase (MAPK) signaling and apoptotic pathways. METHODS To evaluate the effects of moderate and severe maternal hyperglycemia, p...

The ventral nerve cord (vNC) of Drosophila derives from neural stem cells, the neuroblasts (NB) (Poulson, 1950), which delaminate from the ventral neurogenic region of the ectoderm (vNR) in a reproducible spatiotemporal segmental pattern (Hartenstein and Campos-Ortega, 1984; Hartenstein et al., 1987; Doe, 1992b). In the trunk, this pattern of segregating NB does not show any obvious differences...

Using the Korringa-Kohn-Rostoker coherent-potential approximation in the atomic-sphere approximation (KKR-ASA CPA) we have studied the changes in the electronic structure and the superconducting transition temperature Tc in Nb1−xB2 alloys as a function of x. We find that the variation in the electronic structure of Nb1−xB2 alloys as a function of x is consistent with the rigid-band model. Howev...

This research shows two new microalloyed steels with niobium (Nb) for railroad wheels (Nb1 and Nb2) applied on heavy haul transportation (load over 30 tons/axle). The have mixed microstructure composed of pearlite bainite (finished wheel rim section), another one martensite (black section removed machining) obtained by continuous cooling quenching heat treatment followed tempering. bainitic mar...

Reduction of Zr(IV) metallocenium cations with sodium amalgam (NaHg) produces EPR signals assignable to Zr(III) metallocene complexes. The chloro-bridged heterodinuclear ansa-zirconocenium cation [(SBI)Zr(μ-Cl)2AlMe2](+) (SBI = rac-dimethylsilylbis(1-indenyl)), present in toluene solution as its B(C6F5)4(-) salt, thus gives rise to an EPR signal assignable to the complex (SBI)Zr(III)(μ-Cl)2AlMe...

This note develops an encompassing model for two well known variants of the negative binomial model (the NB1 and NB2 forms). We conclude with an application of the proposed model using the data employed in a recent health care study. © 2007 Elsevier B.V. All rights reserved.

An improved methodology of the Zr specimen preparation was developed which allows fabrication of stable Zr nanotips suitable for FIM and AP applications. Initial oxidation of the Zr surface was studied on a Zr nanotip by FIM and on a polycrystalline Zr foil by XPS, both at low oxygen pressure (10(-8)-10(-7)mbar). The XPS data reveal that in a first, fast stage of oxidation, a Zr suboxide interl...

BACKGROUND Homology is a mathematical concept that can be used to quantify degree of contact. Recently, image processing with the homology method has been proposed. In this study, we used the homology method and computed tomography images to quantify emphysema. METHODS This study included 112 patients who had undergone computed tomography and pulmonary function test. Low-attenuation lung regi...

An improved synthesis of 2,5-di(tert-butyl)-3,4-dimethylpyrrole (2-H, HPyr(tBu(2)Me(2))) and a subsequent reaction with KH yield K(Pyr(tBu(2)Me(2))) (2-K) in multi-gram quantities. Four different pyrrolyl (Pyr) and imidazolyl (Im) ligands were used in salt metathesis reactions with [(η(7)-C(7)H(7))ZrCl(tmeda)] (7) to afford a series of azatrozircenes: [(η(7)-C(7)H(7))Zr(η(5)-Pyr(tBu(2)))] (1-Zr...

The structural properties of Tc-Zr binary alloys were investigated using combined experimental and computational approaches. The Tc(2)Zr and Tc(6)Zr samples were characterized by X-ray diffraction analysis, scanning electron microscopy, electron probe microanalysis, and transmission electron microscopy. Our XRD results show that Tc(6)Zr crystallizes in the cubic alpha-Mn-type structure (I43m sp...