Author′s Affiliations: Department of Radiation Oncology, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P. R. China. Corresponding Author: Chao-Nan Qian, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Gua...

Shifting the paradigm of treatment of a locally recurrent nasopharyngeal carcinoma (NPC) from the non-surgical management to a surgical modality has always been a challenge. However, many studies on endoscopic nasopharyngectomy have proven it to be a reliable form of treatment with an excellent outcome. Since 2007, in Sarawak General Hospital, six cases of endoscopic nasopharyngectomy for local...

INTRODUCTION Nasopharyngeal carcinoma is the most common cancer originating from the nasopharynx. OBJECTIVE To study the mechanisms of nasopharyngeal carcinoma, we analyzed GSE12452 microarray data. METHODS GSE12452 was downloaded from the Gene Expression Omnibus database and included 31 nasopharyngeal carcinoma samples and 10 normal nasopharyngeal tissue samples. The differentially express...

Cancer stem cells play a central role in the pathogenesis of nasopharyngeal carcinoma and contribute to both disease initiation and relapse. In this study, cyclooxygenase-2 (COX-2) was found to regulate cancer stem-like side population cells of nasopharyngeal carcinoma cells and enhance cancer stem-like cells' characteristics such as higher colony formation efficiency and overexpression of stem...

BACKGROUND & OBJECTIVE Nasopharyngeal necrosis is an unusual sequelae after radiotherapy for nasopharyngeal carcinoma (NPC). It is mostly managed by conservative treatment, but the efficacy is unsatisfied. This study was to investigate the efficacy of endoscopy-guided debridement on irradiation-related nasopharyngeal necrosis in NPC patients after radiotherapy. METHODS Between Jul. 2006 and M...

Few occupational risk factors have been identified for nasopharyngeal cancer,' although reported associations with poor ventilation,2 smoke, dust, and fumes,3 and exposure to formaldehyde' have suggested that inhalation of carcinogens may play an aetiological part. To provide further leads to occupational risks for this uncommon tumour, we examined on a national basis the association between em...

PURPOSE In childhood cancer survivors, the most common late effect is thyroid dysfunction, most notably subclinical hypothyroidism (SCH). Our study evaluated the risk factors for persistent SCH in survivors. MATERIALS AND METHODS Survivors (n=423) were defined as patients who survived at least 2 years after cancer treatment completion. Thyroid function was assessed at this time and several ye...

Background: Indonesia is a country consisting of islands and oceans that are rich in potential natural resources. Abundant marine products make the Indonesian people empower fish catches into long-lasting salted processed foods. People living coastal areas have high level consumption seafood products, such as fish. Consuming one factors causing incidence nasopharyngeal carcinoma.
 Contents...

background : the present study aimed to report the characteristics and treatment outcomes of five patients with nasopharyngeal adenoid cystic carcinoma and a literature review. methods : between 2000 and 2009, five consecutive patients (4 men, 1 woman) were diagnosed with nasopharyngeal adenoid cystic carcinoma and treated at our institution. three patients had stage iva (t4n0m0) and two patien...

OBJECTIVES To retrospectively evaluate the patients who underwent nasopharyngeal biopsy with imaging and biopsy results, who have or don't have symptoms for nasopharyngeal pathology and to determine the ratio of the nasopharyngeal cancer cases and other pathologic conditions. METHODS In this retrospective study, 983 patients who underwent endoscopic nasopharyngeal biopsy for symptomatic nasop...