OBJECTIVES To determine the association between printing works and nasopharygeal carcinoma as well as other diseases. METHODS Demographic data were obtained for those who had worked in a particular newspaper company since its establishment in 1950. Through access to the data bank of the hospital records of the Labor Insurance Bureau for 1985-94, all workers were identified who had been admitt...

undifferentiated nasopharyngeal corcinoma is frequently misdiagnosed as large cell malignant lymphoma. the aim of this study is to evaluate the diagnostic role of immunohistochemistry and electron microscopy in this tumor. 81 cases of nasopharyngeal carcinoma were studied. patients ranged from 9-90 years in age (mean: 48.5 years). the age incidence curve was bimodal with two peaks in 2-3 and 5-...

Head and neck cancers are a varied group depending on the histopathological and/or anatomical definition one chooses to adopt. The oral cavity, oropharynx, nasopharynx, larynx and hypopharynx are most affected and often the histology is squamous cell carcinoma. Looking at them as a group their incidence worldwide varies dependent on gender, prevalence of smoking anatomic site and geographical r...

Background: Clinacanthus nutans (C.nutans) is a plant consumed as a cancer treatment in tropical Asia. Despite the availability of numerous anecdotal reports, evaluation of active anticancer effects has remained elusive. Therefore we here examined antiproliferative, reactive oxygen species (ROS)-inducing and apoptosis mechanisms of whole plant extracts in different cancer cell lines. Methods: A...

BACKGROUND The hypothalamic-pituitary (h-p) unit is a particularly radiosensitive region in the central nervous system. As a consequence, radiation-induced irreversible, progressively chronic onset hypopituitarism (RIH) commonly develops after radiation treatments and can result in variably impaired pituitary function, which is frequently associated with increased morbidity and mortality. CAS...

BACKGROUND We report our experience in 49 consecutive patients with nasopharyngeal carcinoma who were treated by Intensity-modulated radiation therapy (IMRT) combined with simultaneous but not adjuvant chemotherapy (CHT). METHODS The medical records of 49 patients with histologically proven primary nasopharygeal carcinoma treated with IMRT and concurrent platin-based CHT (predominantly cispla...

PURPOSE To report our experience with intensity-modulated or stereotactic reirradiation in patients suffering from recurrent nasopharyngeal carcinoma PATIENTS AND METHODS The records of 17 patients with recurrent nasopharygeal carcinoma treated by intensity-modulated (n = 14) or stereotactic (n = 3) reirradiation in our institution were reviewed. Median age was 53 years and most patients (n =...

The article in this edition of the journal by Ardern and colleagues illustrates many of the diYculties in formulating and applying guidelines for the control of meningococcal disease. The first problem is the lack of an evidence base. The only published study to support the use of chemoprophylaxis as a control measure was an unblinded, observational study that demonstrated a lower secondary att...

BACKGROUND: Nasopharyngeal carcinoma (NPC) is strongly associated with Epstien-Barr virus (EBV). The metastasis to cervical lymph nodes represents a frequent initial manifestation of NPC. The utility of EBV detection by polymerase chain reaction (PCR) in the diagnosis of occult NPC with cervical metastasis has been reported. Our previous study showed that EBER1 in situ hybridization was somewha...