Hyponatremia (hypo-osmolality) is a disorder of water homeostasis due to abnormal renal diluting capacity. The body limits the degree which serum sodium concentration falls through mechanism called “vasopressin escape”. Vasopressin escape process that prevents continuous decrease in even under conditions sustained high plasma vasopressin levels. Previous reports suggest aldosterone may be invol...

background: vasopressin type 2 receptor (v2r) plays an important role in the water reabsorption in the kidney collecting ducts. v2r is a g protein coupled receptor (gpcr) and the triplet of amino acids aspartate-arginine-histidine (drh) in this receptor might significantly influence its activity similar to other gpcr. however, the role of this motif has not been fully confirmed. therefore, the ...

Purpose: Desmopressin acetate (DDAPV), a synthetic analogue of vasopressin, has been recommended to be used in diabetes insipidus, mild forms of hemophilia and Von Willebrand disease. The DDAPV is available for adminstration via different routes viz. oral, parenteral and nasal, however its dose is very less in case of nasal sprays (20 µg) and parenteral route (4 µg) compared to oral route (0.1 ...

background: the purpose of this study was to assess the vasopressin effect on operation time and the need for electrocauterization frequency and ovarian reserve during laparoscopic stripping of ovarian endometriomas. methods: this was a randomized prospective clinical trial, in which twenty patients between 18-35 years with unilateral endometriomas were randomly divided in two groups of cases a...

Subjects with obesity frequently have elevated serum vasopressin levels, noted by measuring the stable analog, copeptin. Vasopressin acts primarily to reabsorb water via urinary concentration. However, fat is also a source of metabolic water, raising possibility that might role in accumulation. Fructose has been reported stimulate vasopressin. Here, we tested hypothesis fructose-induced syndrom...

the main issues in nasal surgery are to stabilize the nose in the good position after surgery and preserve the cartilages and bones in the favorable situation and reduce the risk of deviation recurrence. also it is necessary to avoid the synechia formation, nasal valve narrowing, hematoma and bleeding. due to the above mentioned problems and in order to solve and minimize them nasal packing, na...

introduction rhinoliths are uncommon nasal masses. they are mineralized masses found within the nasal cavity. they have various clinical presentations. case presentation we report a 13-year-old boy with long-standing nasal obstruction, yellowish nasal discharge and intermittent and minimal nasal bleeding for a few weeks, who had been treated as rhinosinusitis twice. due to the presence of long-...

in crooked noses, the lateral walls are different in shape and symmetry. although the septum is very important to obtain a straight nose, identical and symmetrical lateral walls are needed for a straight looking nasal dorsum. as well as the septum, lateral walls also contribute in nasal skeletal support and stability. thus, obtaining identical and symmetrical lateral walls is important. in orde...

background: nasal continuous positive airway pressure (ncpap) is an effective method of ventilation in newborns with respiratory distress syndrome (rds). using an appropriate nasal skin care protocol is identical to prevention or reduction of nasal skin breakdown in those who receive ncpap. this study aimed to investigate the effectiveness of an evidence-based clinical care protocol on nasal sk...