Microangioarchitecture of the rat parietal cortex was studied by means of scanning electron microscopy and dark field microscopy. The richest supply of blood vessels in the parietal cortex was found in layer III + IV and layer V, where 2 isolated plexuses of microvessels were prominent. The appearance of the plexuses was quite different between motor and sensory areas. In the motor area the cap...

The structure of the capillary plexus in the gas exchange zone in the lungs of five neonates was investigated by electron microscopy and cytochemical techniques. The results show that the capillaries associated with the terminal respiratory saccules are narrow and that they generally possess two to three endothelial cells per cross section. "Seamless" and protoplasmic capillaries were not obser...

T-lymphocytes in the human body routinely undergo large deformations, both passively, when going through narrow capillaries, and actively, when transmigrating across endothelial cells or squeezing through tissue. We investigate physical factors that enable and limit such deformations and explore how passive and active deformations may differ. Employing micropipette aspiration to mimic squeezing...

A Mathematical model for the two phase flow of blood in a narrow capillary surrounded by the tissue has been presented in this paper. We have developed the earlier two phase models of blood flow in capillaries into a model of capillary-tissue fluid exchange system by including porous tissue enclosing the capillary. Blood is not a homogeneous fluid, It is a suspension. The suspended blood cells ...

A mathematical model for blood flow in narrow capillaries under the effect of transverse magnetic field has been investigated. It is assumed that there is a lubricating layer between red blood cells and tube wall. The transient flow of the fit red blood cell surrounded by plasma annulus in the narrow capillary is considered. The analysis of fluid flow between red cell and tube wall, when the ce...

MEDICAL STUDENTS are faced with a challenge to comprehend the enormous complexity of our circulatory systems. There is a gap between courses of anatomy, with detailed description of all normally present macroscopic vessels, and histology, which is focused on microscopic tissue architecture. Both courses leave arterioles, capillaries, and venules almost marginal and are not used to consider the ...

Yap, Belinda, and Roger D. Kamm. Mechanical deformation of neutrophils into narrow channels induces pseudopod projection and changes in biomechanical properties. J Appl Physiol 98: 1930–1939, 2005. First published January 7, 2005; doi:10.1152/japplphysiol.01226.2004.—Neutrophils traversing the pulmonary microcirculation are subjected to mechanical stimulation during their deformation into narro...

The fish gill is the most physiologically diversified vertebrate organ, and its vasculature the most intricate. Application of vascular corrosion techniques that couple high-fidelity resins, such as methyl methacrylate, with scanning electron microscopy yields three-dimensional replicas of the microcirculation that have fostered a better appreciate gill perfusion pathways. This is the focus of ...

Two fused-silica capillaries of considerably different inner diameter (75 and 10 microm) were used for the separation of a set of five standard proteins. The separations were run in acid pH (50 mM phosphate buffer, pH 2.5). Generally better separations (with minor tailing only) were obtained using a standard capillary [27 cm (20 cm effective length)x 75 microm I.D.] in comparison with a narrow ...