نتایج جستجو برای: nanovaccines

تعداد نتایج: 75  

Journal: :Nanomedicine 2017
Marisa E Aikins Joseph Bazzill James J Moon

The development of a successful vaccine against HIV is a major global challenge. Antiretroviral therapy is the standard treatment against HIV-1 infection. However, only 46% of the eligible people received the therapy in 2015. Furthermore, suboptimal adherence poses additional obstacles. Therefore, there is an urgent need for an HIV-1 vaccine. The most promising clinical trial to date is Phase I...

2015
Kathleen A Ross Hyelee Loyd Wuwei Wu Lucas Huntimer Shaheen Ahmed Anthony Sambol Scott Broderick Zachary Flickinger Krishna Rajan Tatiana Bronich Surya Mallapragada Michael J Wannemuehler Susan Carpenter Balaji Narasimhan

H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhydride nanoparticles encapsulating subunit proteins have been shown to enhance humoral and cell-mediated immunity and provide protection upo...

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