نتایج جستجو برای: nanotoxicity

تعداد نتایج: 253  

2011
Yoon-Hee Park Mohammad kazem Koohi Marzie Hejazy Farzad Asadi Sang Hoon Jeong Sang Min Yi Byeong Hyeok Choi Yu-Ri Kim In-Kyoung Kim Meyoung-Kon Kim Sang Wook Son

The human skin equivalent model (HSEM) is well known as an attractive alternative model for evaluation of dermal toxicity. However, only limited data are available on the usefulness of an HSEM for nanotoxicity testing. This study was designed to investigate cutaneous toxicity of polystyrene and TiO2 nanoparticles using cultured keratinocytes, an HSEM, and an animal model. In addition, we also e...

2015
Mingfu Gong Hua Yang Song Zhang Yan Yang Dong Zhang Yueyong Qi Liguang Zou

BACKGROUND GoldMag nanoparticles (GMNPs) possess the properties of colloid gold and superparamagnetic iron oxide nanoparticles, which make them useful for delivery, separation and molecular imaging. However, because of the nanometer effect, GMNPs are highly toxic. Thus, the biosafety of GMNPs should be fully studied prior to their use in biomedicine. The main purpose of this study was to evalua...

2014
Qinghui Zeng Dan Shao Wenyu Ji Jing Li Li Chen Jie Song

Optical nanoparticles (NPs) have the potential to provide new tools for diagnosis and treatment of human diseases, however, their nanotoxicity and biological characteristics are still unclear. Here, we prepared a series of typical NPs (including gold nanospheres, gold nanorods, silver nanopheres, silver triangular nanoplates and quantum dots) with different material and surface chemical modific...

2016
Mingyuan Li Zhiping Li Zhenbo Yang Xingguo Mei

Now safety concern of in vivo nano-carriers toxicity is apparently hindering the extensive applications of nanotechnology in medical sciences. Many studies on the effects of nanomaterials in vitro and in vivo have been published, and revealed that nanomaterials including carbon nanotubes, fullerenes, quantum dots (for example CdS) and oxide nanoparticles (NPs) (for example ZnO, CuO and TiO2) ex...

Journal: :Advanced drug delivery reviews 2012
Thomas Vorup-Jensen Dan Peer

In the process of advancing new technologies, in particular those intended to improve human health, it is not an uncommon observation that its proponents glorify the benefitswith directnesswhile addressing the unresolved matters in vaguer terms. More often, however, real progress requires at the very least the ability to fully appreciate overt or hidden dangers of new medical treatments. In a s...

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