The regeneration of functional tissue in osseous defects is a formidable challenge in orthopedic surgery. In the present study, a novel biomimetic composite scaffold, here called nano-hydroxyapatite (HA)/poly-ε-caprolactone (PCL) was fabricated using a selective laser sintering technique. The macrostructure, morphology, and mechanical strength of the scaffolds were characterized. Scanning elect...

Bevacizumab (Avastin(®)) has been used by ophthalmologists in many countries as an off-label drug for the treatment of wet age-related macular degeneration (AMD). Due to its short half-life necessitating frequent intravitreal injection, a method for sustained delivery is in need. We demonstrated that bevacizumab could be released in a sustained fashion over 90 days from nano- and microspheres f...

A novel high-strength nano-adhesive is demonstrated for fabricating nano- and microfluidic devices. While the traditional plasma sealing methods are specific for sealing glass to poly(dimethylsiloxane) (PDMS), the new method is compatible with a wide variety of polymeric and inorganic materials, including flexible substrates. Additionally, the traditional method requires that sealing occur with...

The reduction of aluminium trichloride by lithium aluminium hydride in the presence of poly(vinylpyrrolidone) or poly(methylmethacrylate) in mesitylene yielded nano aluminium particles in the matrices of respective polymers. Solution phase synthesis methodology was used successfully to produce composites of various Al/polymer ratios. The composites were characterized by powder XRD patterns and ...

Poly(o-anisidine) molybdophosphate was expediently obtained by sol-gel mixing of Poly(o-anisidine) into the inorganic matrices of molybdophosphate, which was allowed to react with silver nitrate to the formation of poly(o-anisidine) molybdophosphate embedded silver nano composite. The composite was characterized by Fourier Transform Infrared Spectroscopy, X-ray powder diffraction, UV-Vis Spectr...

Photosystem II, Watersplitting, Model of H+-Production Using pH indicator dye techniques we have investigated the pH changes in dark-adapted chloro­ plasts following excitation by short flashes. Two types of pH indicator, cresol red and neutral red, were used, to follow the pH changes either inside or outside the thylakoids, or the net change when the membrane was made permeable to protons by u...

Using electrospinning technique, well-aligned poly(azo-ether-imide) (PAEI) nano-fibers and PAEI/multiwalled carbon nanotube (MWCNT) nano-fibers were developed in this effort. Afterwards, polystyrene-b-poly (ethylene-ran-butylene)-b-polystyrene (SEBS) and polyimide-based nano-fiber films were casted. The as-prepared electrospun nanofibers acted as homogeneous reinforcement to enhance the tensile...

BACKGROUND Uremic syndrome is the consequence of the retention of solutes usually cleared by the healthy kidneys. p-Cresol can be considered a prototypic protein-bound uremic toxin. It is conceivable, analogous with drugs, that the non-protein-bound fraction of p-cresol exerts toxicity. This aspect had never been evaluated, nor have the factors influencing the free fraction of p-cresol. METHO...