Three techniques for measuring methotrexate show various cross reactivities with methotrexate-related compounds: "high-pressure" liquid chromatography, by principle, is virtually specific for methotrexate; the enzyme-inhibition assay quantitates methotrexate, methotrexate diglutamate, and methotrexate triglutamate equally well, but has a 10% cross reactivity with 4-amino-4-deoxy-N10-methylptero...

In this paper, fabrication of silicon microchannels with integrated obstacles by using 25 wt.% tetramethylammonium hydroxide (TMAH) aqueous solution at the temperature 80?C is presented and analysed. We studied basic island patterns, which present union two symmetrical parallelograms sides along predetermined crystallographic directions <n10> (2<n<8) <100>. Acute angles were s...

PURPOSE To characterize the recording and analyze the results of the combined cervical and ocular vestibular evoked myogenic potential in individuals without hearing and vestibular complaints. METHODS In this study, 30 individuals without hearing complaints and hearing within normal limits were evaluated. Data were collected through the simultaneous recording of cervical and ocular vestibular...

We present here strong numerical and statistical evidence of the fact that the Smale’s 7th problem can be answered affirmatively. In particular, we show that a local minimum for the logarithmic potential energy in the 2-sphere satisfying the Smale’s conditions can be identified with a computational cost of approximately O(N10).

This paper is concerned with the role of the output-capital ratio in growth models. In the first part we highlight the behaviour of the output-capital ratio along the balanced growth path in the models of Solow (1956) and Romer (1986). In the second part we assess the stability of the ratio for some industrial countries. JEL classification: O40, N10

In grassland ecosystems, N and P fertilization often increase plant productivity, but there is no concensus if fertilization affects soil C fractions. We tested effects of N, P and N+P fertilization at 5, 10, 15 g m-2 yr-1 (N5, N10, N15, P5, P10, P15, N5P5, N10P10, and N15P15) compared to unfertilized control on soil C, soil microbial biomass and functional diversity at the 0-20 cm and 20-40 cm...

We investigated the genomic properties of a rotavirus A strain isolated from diarrheic pheasant poults in Hungary in 2015. Sequence analyses revealed a shared genomic constellation (G23-P[37]-I4-R4-C4-M4-A16-N10-T4-E4-H4) and close relationship (range of nucleotide sequence similarity: VP2, 88%; VP1 and NSP4, 98%) with another pheasant rotavirus strain isolated previously in Germany.

Over the past decade, most important observations of interstellar medium have been made in infrared and radio regions electromagnetic radiation. Of particular interest were GLIMPSE (Galactic Legacy Infrared Midplane Survey Extraordinaire), MIPSGAL WISE (Wide-field Explorer) surveys several areas star formation. Distinctive features view Galactic disk at wavelengths from 3.4 μm to 22 include ion...