The objectives of this study were to evaluate the ability of 14 compounds, which differentially activate human pregnane X receptor (hPXR), to induce CYP2B6 expression and to compare CYP2B6 and CYP3A4 concentration- and time-dependent induction by select inducers. Three primary human hepatocyte preparations were treated daily for 3 days with three concentrations of all compounds. Additional conc...

 Let $R$ be a ring‎, ‎and let $n‎, ‎d$ be non-negative integers‎. ‎A right $R$-module $M$ is called $(n‎, ‎d)$-projective if $Ext^{d+1}_R(M‎, ‎A)=0$ for every $n$-copresented right $R$-module $A$‎. ‎$R$ is called right $n$-cocoherent if every $n$-copresented right $R$-module is $(n+1)$-coprese-nted‎, ‎it is called a right co-$(n,d)$-ring if every right $R$-module is $(n‎, ‎d)$-projective‎. ‎$R$...

MNDO semi-empirical SCF MO calculations are used to study the pyramidal nitrogen atom inversion and configurational equilibria in the title compounds.

let $r$ be a ring‎, ‎and let $n‎, ‎d$ be non-negative integers‎. ‎a right $r$-module $m$ is called $(n‎, ‎d)$-projective if $ext^{d+1}_r(m‎, ‎a)=0$ for every $n$-copresented right $r$-module $a$‎. ‎$r$ is called right $n$-cocoherent if every $n$-copresented right $r$-module is $(n+1)$-coprese-nted‎, ‎it is called a right co-$(n,d)$-ring if every right $r$-module is $(n‎, ‎d)$-projective‎. ‎$r$ ...

mndo semi-empirical scf mo calculations are used to study the pyramidal nitrogen atom inversion and configurational equilibria in the title compounds.

In this article we introduce the notion of n-capable groups. It is shown that every group G admits a uniquely determined subgroup (〖Z^n)〗^* (G) which is a characteristic subgroup and lies in the n-centre subgroup of the group G. This is the smallest subgroup of G whose factor group is n-capable. Moreover, some properties of n-central extension will be studied.

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Let $nin mathbb{N}$. An additive map $h:Ato B$ between algebras $A$ and $B$ is called $n$-Jordan homomorphism if $h(a^n)=(h(a))^n$ for all $ain A$. We show that every $n$-Jordan homomorphism between commutative Banach algebras is a $n$-ring homomorphism when $n < 8$. For these cases, every involutive $n$-Jordan homomorphism between commutative C-algebras is norm continuous.

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