PURPOSE To review the acute and chronic pathological effects of sulfur mustard on the genitourinary system and male fertility. MATERIALS AND METHODS We searched PubMed and Google Scholar to find studies related to the sulfur mustard-induced genitourinary effects and male infertility. Information in the abstracts of non-English related papers as well as those in the proceedings of congresses o...

Introduction: Glutathione S-transferase (GST) is one of the major detoxifiers in alveoli. Polymorphism in GST genes can influence the ability of individuals to suppress oxidative stress and inflammation. The present study was aimed to explore the hypothesis that the genetic polymorphisms of GST T1, M1 and P1 are associated with the severity of the mustard lung in the sulfur mustard-exposed indi...

Uramustine (or uracil mustard, 5-aminouracil mustard, chlorethaminacil), is an bi-functional alkylating nitrogen mustard agent that utilizes a natural product to carry the nitrogen mustard group to a selective metabolite site. The potential for applying uramustine as a therapeutic drug appeared in the 60’s, where its potential as a treatment tool for metastatic Wilms’s tumor was notes (Wilm’s t...

This research aimed to use mustard flour as meat binder in processing of beef burgers instead of soybean flour (SF). Effect of addition mustard flour from two mustard varieties, yellow (Sinapis alba) (YMF) or brown (Brassica juncea) (BMF) mustard seed flour at different levels (3 and 6%) on the quality characteristics of beef burger patties was studied. The incorporation of mustard flour as a b...

Allergy to mustard seeds has been reported for years, in many cases as very strong anaphylactic reactions. Recent studies have shown that this allergy is increasing and that mustard allergens can be considered among the most important food allergens, especially in countries where the consumption of mustard seed is high. Clinical studies describing hypersensitivity to mustard are reviewed in thi...

As one of the most important vesicant agents, the destructive properties of mustards on the skin, eyes and respiratory system, combined with a lack of antidote, makes them effective weapons. Such weapons are inexpensive, easily obtainable and frequently stockpiled. Sulphur mustard (mustard gas) has been used as a chemical warfare agent in at least 10 conflicts. In this article, the use of musta...

Most herbivorous insect species are restricted to a narrow taxonomic range of host plant species. Herbivore species that feed on mustard plants and their relatives in the Brassicales have evolved highly efficient detoxification mechanisms that actually prevent toxic mustard oils from forming in the bodies of the animals. However, these mechanisms likely were not present during the initial stage...

Aims: To present 12 new variants of uracil mustard having drug-like properties and cytotoxic functional group, by utilizing uracil mustard (uramustine) as a lead compound. Utilize rigorous substructure and similarity of a molecular scaffold to determine drug like variants. Physicochemical properties determined indicate the variants have favorable drug-likeness. Study Design: Conduct molecular d...

Background: Sulfur mustard gas is a chemical agent that has been used in many wars, especially in Iran-Iraq war. This chemical agent affects many organs including lungs, eyes and skin, causing numerous acute and chronic lesions including erythema and hyperpigmentation, respectively. This study was conducted to evaluate erythema and melanin in subjects with a history of exposure to sulfur ...

Mustard leaf (Brassica juncea (L.) Czern.) using as material of a traditional fermented vegetable food (Kimchi) in Korea, is one of the important vegetables. Two cultivars of mustard (red and green) were grown in the experimental farm of Chungnam National University and allowed them to grow until flowering stage. In this study, the variability of γ-aminobutyric acid (GABA) content and mRNA tran...