Background: The continuous infusion of the loop diuretic, bumetanide, has been shown to be effective in the treatment of severe refractory edema. Musculoskeletal symptoms have been reported with bumetanide following both oral and intermittent IV bolus therapy. It has been suggested that these adverse effects do not occur with continuous infusion. We describe, however, a series of patients with ...

Pseudopseudohypoparathyroidism (PPH) is a rare genetic disorder characterized by multiple musculoskeletal anomalies and normal serum calcium, phosphate, and parathyroid hormone levels. Although the musculoskeletal manifestations of PPH are well known, little has been reported on the management of orthopedic problems. We report a case of total knee arthroplasty (TKA) performed in a patient with ...

Almost one out of five people, including children, suffers from musculoskeletal disorders. It is the second leading cause disability worldwide. affects system’s major areas, represented by shoulder, forearm, and wrist. causes severe pain, joint noises, disability. To detect abnormality, radiologist analyzes patient’s anatomy through X-rays different views projections. automatically diagnose abn...

The patients with acute leukemia occasionally present with musculoskeletal symptoms initially, including bone pain, joint pain, muscular pain, and functional impairment. Without abnormal findings of peripheral blood cell counts or smear, the correct diagnosis tends to be delayed. Magnetic resonance imaging is often performed to examine musculoskeletal abnormalities; it can simultaneously reveal...

OBJECTIVE To study the frequency, the clinical features and laboratory exams of patients with musculoskeletal symptoms at the onset of acute leukemia. METHODS Retrospective, descriptive study including patients diagnosed with acute leukemia, and treated at the Institute of Pediatric Oncology of UNIFESP, carried out from November 1999 to February 2000. The data on musculoskeletal complaints we...

Background: Diabetes mellitus is a chronic metabolic disorder with vast social and economic consequences an ageing population obesity due to sedentary lifestyle are one of the foremost reasons for development type 2 diabetes mellitus. Aim current study was ascertain burden respiratory function abnormalities in diabetic subjects its correlation symptom hba1c non-smokers. Methods: This cross-sect...

Snapping phenomena result from the sudden impingement between anatomical and/or heterotopical structures with subsequent abrupt movement and noise. Snaps are variously perceived by patients, from mild discomfort to significant pain requiring surgical management. Identifying the precise cause of snaps may be challenging when no abnormality is encountered on routinely performed static examination...

A further family carrying the abnormality for malignant hyperpyrexia has been studied over four generations. The carriers with one exception have been identified by creatine phosphokinase estimations. In one branch of this family two grandchildren exhibit multiple musculoskeletal abnormalities and in addition a high creatine phosphokinase. The rest of the family was clinically normal though man...

BACKGROUND Aphallia or penile agenesis is a rare malformation accompanying with no phallus. This anomaly is extremely rare with abnormality of urogenital system and psychological consequences. Its outbreak is estimated 1 out of 10-30 million births. CASE Reviewing 3 cases of male external genitalia agenesis, which associated with multiple anomalies of musculoskeletal, cardiovascular and genit...