ependymomas are glial tumors originate from ependymal cells lining the ventricles and the central canal of the spinal cord. two thirds of ependymomas arise in the infratentorial or intraventriclesandone-third aredetected in supratentorial area. however supratentorial “cortical” ependymomas are veryuncommon. ependymomas are usually infratentorial, intraventricular tumor, including 2–9% of all ce...

in 1890, coley observed that cancer patients who developed infections had smaller tumors. from this, he developed coley’s toxin and treated tumors with injections of infectious materials. in 1960s,  mahaley used monoclonal antibodies to treat central nervous system(cns)  tumors, that research and clinical investigations in brain tumor immunotherapy became a serious undertaking. there are severa...

brain tumors in elderly are increasing as the number of people, who comprise the older population, does.about half of the patients with brain tumors appear to be over 60 years of age.in this review article, glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential di...

frequency of common etiologies of adult onset epilepsy is different in various studies. the aim of this study is to evaluate the frequency of common ‎etiologies of late adult onset epilepsies. ‎ all patients referred to razi and imam khomeini hospitals ‎in the year 2003 with at least two seizure attacks beginning after age of 50 were evaluated. in the majority of cases neuroimaging, electroence...

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Glioblastoma is a destructive form of brain tumor that kills most patients within two years of diagnosis.Treatments for glioblastoma include the usual options of surgery, radiation therapy and chemotherapy, but there is no effective treatment. The tumors are capable of spreading tendrils out into the brain and it can grow back in a matter of months after being removed. The cancer stem cell...

Abstract Background: Brain tumors are fatal malignancies which are frequently associated with psychiatric and behavioural manifestation that should be noticed. Studies suggest that the primary psychiatric dysfunctions are associated with brain tumors in 47-94 % of cases. Case report: A 26-year single woman with neuropsychic symptoms was under the drug therapy with antipsychotic, as well as sed...

Abstract Approximately 50% of all brain metastasis cases originate from primary lung tumors. Whole-brain radiation therapy (WBRT) is a common treatment for patients with multiple metastases, but rarely survive longer than one year after diagnosis. Recent studies demonstrate improved outcomes combinatorial radiotherapy and immunotherapy, the optimal timing immunotherapy administration unclear. E...

Introduction: Due to nuclear interactions between the tissues and high-energy protons, the particles, including neutrons, positrons, and photons arise during proton therapy. This study aimed at investigating the dose distribution of proton and secondary particles, such as positrons, neutrons, and photons using the Monte Carlo method. Material and Methods:<...