This study describes the effect of ethanol and the presence of poly(ethylene) glycol (PEG) lipids on the interaction of nucleotide-based polyelectrolytes with cationic liposomes. It is shown that preformed large unilamellar vesicles (LUVs) containing a cationic lipid and a PEG coating can be induced to entrap polynucleotides such as antisense oligonucleotides and plasmid DNA in the presence of ...

Bisulfite has been shown to induce leakage of encapsulated substances from liposomal vesicles. The bisulfite induced leakage of either DNP-tyrosine, potassium ferricyanide, or [3H]glycine was observed to be greater with lipsomes composed of phospholipids containing unsaturated fatty acids. The leakage of encapsulated substances from liposomes was found to be concentration dependent when incubat...

Abstract The newest method to maintain better bioavailability of antioxidant compounds in the human digestive process is encapsulation using liposomes. liposomes used were lecithin from soybean seeds and L-α-Phosphatidylcholine. Furthermore, curcumin β-carotene encapsulated soy SC-CO2 with 100% ethanol, aquadest 50% v/v ethanol at 50°C, 60°C, 70°C pressure 15 MPa, 20 MPa 25 by ultrasonication f...

The partitioning of a homologous series of n-alkyl p-aminobenzoates into the lipid bilayer is dependent not only on their physicochemical properties but also on liposome type. Partitioning studies with this homologous series demonstrate the effect of alkyl chain length on partitioning in DPPC multilamellar liposomes (MLV) and DPPC MLV extruded through 1 or 0.4 pm polycarbonate filters. A genera...

Abstract The Indian system of medicine, Ayurveda employs Bacopa monnieri extract (BME) for memory enhancement. This study attempts to prepare and test a more potent formulation by incorporating BME in nanovesicles. BME-loaded liposomes bilosomes (bile salt-stabilized liposomes) were formulated using soy phosphatidylcholine. Liposomes had homogeneous size distribution an average 285.7 nm 84 nm, ...

objective to determine and compare the spf (sun protection factor) and moisturizing effects of the liposomal and conventional lotion formulations containing octyl methoxycinnamte (omc) as a sunscreen by in vivo methods. materials and methods the multilamellar liposomes (mlvs) containing omc were prepared by fusion method and o/w emulsion was prepared as fda standard sunscreen method. the spfs o...

The influence of n-decane on the lipid bilayer thickness and on the frequency of lateral collisions of the excimer fluorescence probe 1-pyrenedodecanoic acid was studied in unilamellar and multilamellar egg yolk phosphatidylcholine (EYPC) model membrane systems. In multilamellar systems, the n-decane molecules are located predominantly in the bilayer center between apposing monolayers. Up to n-...

The effects of ionic liquids on model phospholipid membranes were studied by small-angle X-ray scattering, dynamic light scattering (DLS) and zeta potential measurements. Multilamellar 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine liposomes and large unilamellar vesicles composed of l-α-phosphatidylcholine (eggPC) and l-α-phosphatidylglycerol (eggPG) (80:20mol%) or eggPC, eggPG, and choleste...