background: acute normovolemic hemodilution is an available technique to decrease the side effects of allogenic blood transfusion. the aim of this study was to compare acute normovolemic hemodilution with allogenic blood transfusion in adult patients who were scheduled for femoral fracture surgery. methods: in this randomized controlled trial, 50 patients were randomly allocated into two equal ...

BACKGROUND Alloimmunization is an adverse effect of blood transfusions. In Chile, alloimmunization frequency is not established, and for this reason the aim of this study was to investigate the prevalence and specificity of red blood cell (RBC) alloantibodies in Chilean transfused subjects. METHODS Records from 4,716 multi-transfused patients were analyzed. In these patients, antibody screeni...

background: the development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. also, autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. we studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in ilam province...

Background: Recurrent blood transfusion is a common treatment in patients with thalassemia. The development of antibodies against red blood cell (RBC) antigens complicates RBC cross-matching, enhances the in vivo destruction of transfused cells, accelerates tissue iron overloading, delays the provision of safe transfusion, and reduces health-related quality of life. Materials and Methods: In t...

Background: Transfusion-transmi!ed infec"ons (TTIs) con"nue to be a problem in many parts of the world and mul"-transfused pa"ents are at a par"cularly increased risk for TTIs. The aim of this study was to determine the prevalence of Hepa""s C, Hepa""s B, and human immunodeficiency virus (HIV) infec"ons among mul"-transfused pa"ents in Khuzestan Province. Materials and Methods: A cross-sec"onal...