BACKGROUND Many patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) have had recent healthcare interventions prior to developing ALI/ARDS. OBJECTIVE To determine the timing of ALI/ARDS onset in relation to hospital admission and other healthcare interventions. METHODS We conducted a population-based observational cohort study with a validated electronic surv...

Receptor for advanced glycation end-products (RAGE) is a marker of alveolar type I cells and is elevated in the pulmonary edema fluid of patients with acute lung injury (ALI). We tested the hypothesis that RAGE in the bronchoalveolar lavage (BAL) would be elevated in experimental models of direct ALI characterized by alveolar epithelial cell injury. We developed ELISA measurements for RAGE and ...

INTRODUCTION Acute lung injury (ALI) can result from various insults to the pulmonary tissue. Experimental and clinical data suggest that spontaneous breathing (SB) during pressure-controlled ventilation (PCV) in ALI results in better lung aeration and improved oxygenation. Our objective was to evaluate whether the addition of SB has different effects in two different models of ALI. METHODS F...

Broad research interests and related applications: My research is in the area of stochastic systems, computational methods for sensing, estimation, and control problems, with a focus on robotic systems. In real-world systems, uncertainty (both in the system model and sensory readings) is omnipresent. A few of the vast set of applications for this research include (i) Motion planning for mobile ...

| 2017 | 1 Seyed-Hossein Abtahi1,2, Mohammad-Ali Abtahi1,2, Seyed Ali Akbar Mortazavi1,2, Hamidreza Jahanbani-Ardakani2,3,4, Mehdi Mazloumi5 1Department of Ophthalmology, School of Medicine, Isfahan University of Medical Sciences, 2Isfahan Eye Research Center, Isfahan University of Medical Sciences, 3Medical School, Isfahan University of Medical Sciences, 4Isfahan Medical Students Research Cent...

We have solved the crystal structure of an alI-RNA hammerhead ribozyme having a single 2'-O-methyl cytosine incorporated at the active site to prevent cleavage. The conditions used differ from those in another recent solution in four significant ways: f irst, it is an alI-RNA ribozyme rather than a DNA-RNA hybrid; second, the connectivity of the ribozyme backbone strands is different; third, th...

RATIONALE We hypothesise that elafin levels in acute lung injury (ALI) decrease over time due, in part, to proteolytic degradation as observed in other lung diseases. OBJECTIVES The aim of this study was to characterise temporal changes in elafin concentration in patients with ALI and to evaluate whether a decrease in elafin levels is due to elevated protease activity. METHODS Bronchoalveol...

Acute lung injury (ALI) associated with systemic inflammatory response syndrome (SIRS) is a systemic complication following subarachnoid hemorrhage (SAH), but the incidence and influence on prognosis are unclear. The incidences of SIRS and ALI were surveyed in a prospective multicenter study of 96 patients admitted for SAH between December 2004 and June 2007. Hunt and Hess grade and Glasgow Out...

Automatic Language Identification (ALI) is the problem of automatically identifying the language of an utterance through the use of a computer. In 1977, House and Neuburg proposed an approach to ALI which focused on the phonotactic constraints of different languages. Their work suggested that simple language models could be used effectively for language identification if an accurate phonetic re...

This a rare case of adenoid hypertrophy in a 23 years old Saudi non-smoker female, who presented with severe bilateral nasal obstruction, mouth breathing, anterior nasal discharge, snoring for the last 7 months. The nasopharynx was examined by flexible nasopharyngoscope, which showed a big mass occupying the nasopharynx. Under general anesthesia, adenoidectomy was performed. Immediately after t...