نتایج جستجو برای: mucosal defense

تعداد نتایج: 112516  

2017

Start studying Chapter 47 Text. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Results. Gastroscopy revealed 38 diffuse lesions (14 antral gastritis, 19 pangastritis, and 5 diffuse antral vascular ectasia) and 25 localized lesions (14 erosions. III. MUCOSAL DEFENSE “Mucosal defense” is a term used to describe the various factors and components that permit the m...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Jeremy J Barr Rita Auro Mike Furlan Katrine L Whiteson Marcella L Erb Joe Pogliano Aleksandr Stotland Roland Wolkowicz Andrew S Cutting Kelly S Doran Peter Salamon Merry Youle Forest Rohwer

Mucosal surfaces are a main entry point for pathogens and the principal sites of defense against infection. Both bacteria and phage are associated with this mucus. Here we show that phage-to-bacteria ratios were increased, relative to the adjacent environment, on all mucosal surfaces sampled, ranging from cnidarians to humans. In vitro studies of tissue culture cells with and without surface mu...

2012
Wu Li Guangcun Deng Min Li Xiaoming Liu Yujiong Wang

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is one of the world's leading infectious causes of morbidity and mortality. As a mucosal-transmitted pathogen, Mtb infects humans and animals mainly through the mucosal tissue of the respiratory tract. Apart from providing a physical barrier against the invasion of pathogen, the major function of the respiratory mucosa ...

2015
Hetron Mweemba Munang’andu Stephen Mutoloki Øystein Evensen

Mucosal organs are principle portals of entry for microbial invasion and as such developing protective vaccines against these pathogens can serve as a first line of defense against infections. In general, all mucosal organs in finfish are covered by a layer of mucus whose main function is not only to prevent pathogen attachment by being continuously secreted and sloughing-off but it serves as a...

2011
Sara K Linden Michael A McGuckin

The human body encounters pathogenic bacteria every day although establishment of infections after such contacts is rare. The skin and mucosal surfaces, which comprise the barrier between the body and the external milieu, are the first lines of defense, and colonization of these surfaces is normally the first step in bacterial disease. As a physical barrier, the skin is reinforced by dry, sligh...

Journal: :Toxicologic pathology 1988
J W Freston

Both genetic and nongenetic factors predispose to ulcer diathesis. At the mucosal level ulcers result from an imbalance between aggressive factors and mucosal defense. Ulcer therapy reduces aggressive forces, bolsters defense, or both. Gastric acid, the major aggressive factor, may have its secretion inhibited or it may be partially neutralized by antacids. H2 receptor antagonists competitively...

Journal: :Journal of immunology 2011
Melinda M Zaragoza Sumathi Sankaran-Walters Don R Canfield Jason K S Hung Enrique Martinez André J Ouellette Satya Dandekar

Gastrointestinal mucosa is an early target of HIV and a site of viral replication and severe CD4(+) T cell depletion. However, effects of HIV infection on gut mucosal innate immune defense have not been fully investigated. Intestinal Paneth cell-derived α-defensins constitute an integral part of the gut mucosal innate defense against microbial pathogens. Using the SIV-infected rhesus macaque mo...

خسروی, نسترن,

  NEC (Necrotizing Enterocolitis) is an increasing clinical burden to patients, families, and the neonatology health care team. Although the diagnosis is straightforward, the morbidity and mortality associated with the disease are not improving. Risk factors of prematurity, formula feeding, intestinal ischemia/hypoxia, and bacterial colonization accentuate the imbalance toward mucosal stress wi...

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