Recently, manufacturers are taking a hybrid approach between MTS and MTO. However, most of literature research on production planning concentrates principally on MTS systems. The MTO area has not received the same degree of attention. There are only some research papers which are based on queueing network models that explicitly talk about the Lot Sizing Problem (LSP) in MTO sector. This paper p...

Mineraloils have long been utilizedin industriesas machining lubricants, which contributed to theirdepletion and hick in priceandbeing non-biodegradable, harmful the environment,and risk health.Plant-basedoil is more biodegradable, renewable, environmentally friendlyas a green alternative.However, their crudestate, plant-based oilsare not up par with standard mineral oil used lubricationin term...

This paper addresses one of the most important issues have been considered in hybrid MTS/MTO production environments. To cope with the problem, a mathematical programming model is applied from a tactical point of view. The model is converted to a fuzzy goal programming model, because a degree of uncertainty is involved in hybrid MTS/MTO context. Finally, application of the proposed model in an ...

Protein subunit vaccines present a compelling new area of research for control of tuberculosis (TB). Based on the interaction between Mycobacterium tuberculosis and its host, five stage-specific antigens of M. tuberculosis that participate in TB pathogenesis--Rv1813, Rv2660c, Ag85B, Rv2623, and HspX--were selected. These antigens were verified to be recognized by T cells from a total of 42 whol...

Multidrug resistance (MDR) is a severe obstacle to successful chemotherapy due to its complicated nature that involves multiple mechanisms, such as drug efflux by transporters (P-glycoprotein and breast cancer resistance protein, BCRP) and anti-apoptotic defense (B-cell lymphoma, Bcl-2). To synergistically and completely reverse MDR by simultaneous inhibition of pump and non-pump cellular resis...

The number of people suffering from symptoms sensitive skin has been growing. Their main pains are specified as dryness and chronic itch. Recent studies showed that Substance P (SP) Neurokinin 1 receptor (NK1R) on the C nerve fibers related to Focusing this pathway, we discovered maltotetraose (MTO), a type polysaccharide, alleviated itch skin. Single-center, open-label clinical trials formulat...

Increasing cost pressures have led supply chain managers to focus on running increasingly lean and efficient supply chains, with minimal inventory. Indeed, more and more firms are relying on pull or make-toorder (MTO) supply chains to minimize cost and waste. At the same time, increasing competitive pressures are leading to an increased emphasis on customer service. An important element of cust...

The Moving to Opportunity (MTO) housing experiment has proven to be an important intervention not just in the lives of the poor, but in social science theories of neighborhood effects. Competing causal claims have been the subject of considerable disagreement, culminating in the debate between Clampet-Lundquist and Massey and Ludwig et al. in this issue. This article assesses the debate by clar...

One of the growing production strategies is hybrid Make-To-Stock (MTS)/ Make-To-Order (MTO), since this strategy benefit from the both well-know strategies MTS and MTO. Among handful research papers in the field of hybrid production context, no researches have been devoted to aggregate production planning level. Therefore, this paper addresses aggregate production planning from a tactical point...