نتایج جستجو برای: mtnr1a gene

تعداد نتایج: 1141382  

Journal: :iranian journal of biotechnology 2006
heydar ghiasi mohamad reza nasiry ali reza heravi mousavi abdol azim mousavizadeh ali javad manesh

the genotypes of the melatonin receptor 1a (mtnr1a) were determined by pcr-rflp in the native iranian shall  and karakul breeds of sheep . blood samples were collected from 60 karakul and 50 shall breeds. genomic dna was extracted based on the guanidin thiocyanate-slica gel method. after pcr reaction, pcr products were digested by the mnl1 restriction enzyme. the mtnr1a locus had two genotypes ...

I. Afrooznia M. Zandi, M.H. Hadi Tavatori M.R. Sanjabi

The objective of this study was to evaluate the relationship between polymorphism at the MnlI site of MTNR1A gene and production traits of Shal and Romanov crossbreeding. The crossbreeding between Shal and Romanov was done on 600 Shal ewes. For this reason, Shal ewes were laparoscopically and artificially inseminated with the semen of Romanov breed. For the preparation of genomic DNA, a total o...

2017
Jiunn-Diann Lin Shun-Fa Yang Yuan-Hung Wang Wen-Fang Fang Ying-Chin Lin Bing-Chun Liou Yuh-Feng Lin Kam-Tsun Tang Chao-Wen Cheng

BACKGROUND Melatonin plays an important role in immunity and has been linked to autoimmune diseases. Possible associations of single-nucleotide polymorphisms (SNPs) of melatonin receptor type 1A (MTNR1A) and 1B (MTNR1B), with autoimmune thyroid disease in an ethnic Chinese (i.e., Taiwanese) population were examined. MATERIALS AND METHODS Totally, 83 Hashimoto's thyroiditis patients, 319 Grave...

Abdol Azim Mousavizadeh Ali Javad Manesh Ali Reza Heravi Mousavi Heydar Ghiasi, Mohamad Reza Nasiry,

The genotypes of the melatonin receptor 1A (MTNR1A) were determined by PCR-RFLP in the native Iranian Shall  and karakul breeds of sheep . Blood samples were collected from 60 karakul and 50 Shall breeds. Genomic DNA was extracted based on the Guanidin Thiocyanate-slica gel method. After PCR reaction, PCR products were digested by the Mnl1 restriction enzyme. The MTNR1A locus had two genotypes ...

2010
Pauline Chaste Nathalie Clement Oriane Mercati Jean-Luc Guillaume Richard Delorme Hany Goubran Botros Cécile Pagan Samuel Périvier Isabelle Scheid Gudrun Nygren Henrik Anckarsäter Maria Rastam Ola Ståhlberg Carina Gillberg Emilie Serrano Nathalie Lemière Jean Marie Launay Marie Christine Mouren-Simeoni Marion Leboyer Christopher Gillberg Ralf Jockers Thomas Bourgeron

Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration of the melatonin pathway has been reported in circadian disorders, diabetes and autism spectrum disorders (ASD). However, very little is known about the genetic variability of melatonin receptors in humans. Here, we sequenced the melatonin receptor MTNR1A and MTNR1B, genes coding for MT1 and MT2 r...

Genotypes for melatonin receptor type 1A (MTNR1A) and Calpastatin (CAST) were determined by enzymatic digestion of PCR products and Calpain(CAPN) genotype detected by PCR-SSCP method in Iranian Karakul sheep. Blood samples were collected from 100 purebred Karakul sheep. The extraction of genomic DNA was based on guanidinium thiocyanate- silica gel method. PCR amplicons were digested with restri...

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