Methylthioadenosine (MTA) is a precursor of the methionine salvage pathway and has been shown to have anti-inflammatory properties in various models of acute and chronic inflammation. However, the anti-inflammatory properties of MTA in models of intestinal inflammation are not defined. We hypothesized that orally administered MTA would be bioavailable and reduce morbidity associated with experi...

Mineral trioxide aggregate (MTA) has been recommended for various uses in endodontics. To understand the effects of MTA on alveolar bone, we examined whether MTA induces osteoblastic differentiation using MC3T3-E1 cells. MTA enhanced mineralization concomitant with alkaline phosphatase activity in a dose- and time-dependent manner. MTA increased production of collagens (Type I and Type III) and...

The scheduling of antifolate antitumor agents, including the new multitargeted autofolate LY231514 (MTA), with 5-fluorouracil was explored in the human MX-1 breast carcinoma and human H460 and Calu-6 non-small cell lung carcinoma xenografts to assess antitumor activity and toxicity (body weight loss). Administration of the antifolate (methotrexate, MTA, or LY309887) 6 h prior to administration ...

AN IN VITRO COMPARISON OF THE SETTING OF MTA WITH AND WITHOUT THE APPLICATION OF A MOIST COTTON PELLET Craig D. Johnson, D.D.S. Marquette University, 2010 Introduction: The purpose of this study was to compare the setting of MTA with and without the application of a moist cotton pellet. Methods: Fifty samples of MTA were mixed according to manufacturer’s instructions, placed with an amalgam car...

سابقه و هدف: امروزه صنعتی شدن توسعه شهرنشینی باعث آلودگی هوا در اکثر کلان‌شهرهای جهان شده است سالانه میلیون­ ها نفر به ­علت جان خود را از دست می­ دهند. ﺑﺎ ﺗﻮﺟﻪ ﺑﻪ ﻣﺤﺪود ﺑﻮدن ﺷﺒﻜﻪ اﻳﺴﺘﮕﺎه‌ﻫﺎى ﭘﺎﻳﺶ آﻻﻳﻨﺪه‌ﻫﺎى ﻫﻮا ﻏﻴﺮ اﻗﺘﺼﺎدى اﻓﺰاﻳﺶ ﺗﻌﺪاد این اﻳﺴــﺘﮕﺎه‌ﻫا سطح شهرها، دﺳﺖ‌ﻳﺎﺑﻰ ﭘﻮﺷــﺶ ﻣﻜﺎﻧﻰ زﻣﺎﻧﻰ ﻣﻨﺎﺳــﺐ برای ﻧﺸﺎن دادن ﺗﻐﻴﻴﺮات ﻏﻠﻈﺖ ذرات آلاینده ﺑﺴﻴﺎر دﺷﻮار اﺳﺖ. بر اساس پژوهش حاضر با هدف تهیه نقشه ­ها...

Objective. The aim of this in vitro study was to evaluate the long-term fracture resistance of simulated human immature permanent teeth filled with BioAggregate™ (BA), mineral trioxide aggregate (MTA), and EndoSequence® Root Repair Material (ERRM). Material and Methods. 40 teeth, simulated to average root length of 13 ± 1 mm (Cvek's stage 3), were included in the study. The teeth were randomly ...

Objective Mineral trioxide aggregate (MTA) cements contain two types of particles, namely Portland cement (PC) (nominally 80% w/w) and bismuth oxide (BO) (20%). This study aims to determine the particle size distribution (PSD) of PC and BO found in MTA. Materials and methods The PSDs of ProRoot MTA (MTA-P) and MTA Angelus (MTA-A) powder were determined using laser diffraction, and compared to s...