Background: Pain can interfere with the daily functioning of patients with Multiple Sclerosis (MS). Furthermore, sleep disturbance is a common symptom of MS. The dialectical behavior therapy program is presented as a detailed structured treatment program that was demonstrated that has effects on the treatment of psychosomatic disorders such as pain and sleep disorders. Objectives: To investiga...

objective: multiple sclerosis (ms) is one of the leading neurodegenerative causes of physical disability world-wide. genetic aberrations of autoimmunity pathway components have been demonstrated to significantly influence ms development. cluster of differentiation 58 (cd58) is pertained to a group of genes which had been assayed in several recent association studies. given the significance of c...

significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. the most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. during the last ten years, this view was subsequently changed and the term neuromyelitis optica...

Significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. The most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. During the last ten years, this view was subsequently changed and the term neuromyelitis ...

Multiple Sclerosis (MS) is an autoimmune disease, which is characterized by demyelination and neuroinflammation. Extracellular Matrix (ECM) have important role in the central nervous system (CNS). Alterations are happening to the ECM after the CNS disorder like MS, Alzheimer and other neural injury. Tenasin-C (TnC) is a glycoprotein that is highly expressed in inflammatory conditions of the CNS...

Background: Lack of sufficient information on the mechanism of plasma exchange (PE) therapy in multiple sclerosis (MS), has limited this treatment to individual patients with severe relapses who have been refractory to other treatments. This is while PE is used very successfully as a first-line standard treatment in many other neuro-immune disorders. Recent data suggest that Treg/Th17 counterb...

background: lack of sufficient information on the mechanism of plasma exchange (pe) therapy in multiple sclerosis (ms), has limited this treatment to individual patients with severe relapses who have been refractory to other treatments. this is while pe is used very successfully as a first-line standard treatment in many other neuro-immune disorders. recent data suggest that treg/th17 counterba...