Background: The study of specific genes expressed in the testis is important to understanding testis development and function. Spermatogenesis is an attractive model for the study of gene expression during germ cell differentiation. Spermatogenesis associated-19 (Spata-19) is a recently-identified important spermatogenesis-related gene specifically expressed in testis. Its protein product is in...

Single-cell RNA (scRNA) analysis has made it possible for researchers to investigate various biological processes, including development and differentiation. Previous scRNA studies on developing mouse skin have helped shed light the molecular cellular processes involved in regeneration of this tissue. However, these primarily focused either fetal stage or early postnatal period, leaving a gap o...

background: the study of specific genes expressed in the testis is important to understanding testis development and function. spermatogenesis is an attractive model for the study of gene expression during germ cell differentiation. spermatogenesis associated-19 (spata-19) is a recently-identified important spermatogenesis-related gene specifically expressed in testis. its protein product is in...

introduction: doxorubicin is frequently used for treatment of several types of cancer. doxorubicin cardiac toxicity has limited the use of this drug. corticosteroids may prevent doxorubicin induced cardiotoxicity. therefore the aim of this study was to evaluate mouse embryonic stem cells derived cardiomyocytes as a model to evaluate the effect of doxorubicin and dexamethasone. methods: mouse em...

Cell culture using a 3D method provides Various cell strategies have been developed synthetic or biological materials; most existing publications use many reagents. Bioscaffold from mouse embryonic fibroblast (MEF) enhances attachment, interaction, and production of growth factors. Since bioscaffolds could maintain stimulate pluripotency stem cells, we conducted this study to prove bioscaffold ...