Hepatitis B virus (HBV) infection is the most common cause of end stage liver disease in Iran and in Golestan province. Large-scale population-based prospective cohort studies with long term follow-up are the method of choice to accurately understand the natural course of HBV infection. To date, several studies of HBV epidemiology, natural history, progression to cirrhosis and association with ...

Soil is well known to support the transient or ongoing existence of kerathophilic fungi and potential sources of infection for humans and animals. Fifty soil samples were collected from various areas of forests and farmyards at Golestan Province in the north part of Iran to determine the prevalence of keratinophilic fungi and dominant species. A total of 357 fungal colonies including 13 genera ...

OBJECTIVES To investigate the impact of gender on multimorbidity in northern Iran. DESIGN A cross-sectional analysis of the Golestan cohort data. SETTING Golestan Province, Iran. STUDY POPULATION 49 946 residents (age 40-75 years) of Golestan Province, Iran. MAIN OUTCOME MEASURES Researchers collected data related to multimorbidity, defined as co-existence of two or more chronic disease...

OBJECTIVES Recent studies have suggested the occurrence patterns and related diet factor of esophagus cancer (EC) and gastric cancer (GC). Incidence of these cancers was mapped either in general and stratified by sex. The aim of this study was to model the geographical variation in incidence of these two related cancers jointly to explore the relative importance of an intended risk factor, diet...

The earliest reports of high incidence of oesophageal cancer (OC) in the northern parts of Iran date back to the early 1970s. A population-based cancer registry was established in 1969 as a joint effort between Tehran University and the International Agency for Research on Cancer (IARC). This registry confirmed the high incidence of OC in the eastern portion of the Caspian Sea littoral, in the ...

AIM To define the sub site distribution of upper gastrointestinal cancers in three provinces of Iran. METHODS The study was carried out in three provinces in Iran: Ardabil, Golestan, and Tehran. In Arbabil and Golestan, the data was collected from the sole referral center for gastrointestinal cancers and the local cancer registry. For Tehran province, data from two major private hospitals wer...

BACKGROUND Zoonotic cutaneous leishmaniasis (ZCL) is one of the most important vector-borne diseases in Iran. Wild Rodents play as a reservoir. The main aim of this study was to determine spatial analyses of the relationship between rodent's active burrows and Incidence of ZCL in Golestan Province, north east of Iran. METHODS The cross-sectional study was conducted in 59 rural districts in Go...