Background: Rad51 is a protein with critical role in double strand break repair. Down-regulation of this protein has a significant effect in radiosensitivity of some cell lines like prostate carcinoma. Compared to monolayer cell culture model, the spheroids are more resistant to radiation. The aim of the current study was to determine the Rad51 protein level in DU145 spheroids, and monol...

Two dimensional (2D) gamma-boron (γ-B28) thin films have been firstly reported by the experiments of the chemical vapor deposition in the latest study. However, their mechanical properties are still not clear. Here we predict the superhigh moduli (785 ± 42 GPa at 300 K) and the tension-induced phase transition of monolayer γ-B28 along a zigzag direction for large deformations at finite temperat...

To improve graphene-based multifunctional devices at nanoscale, a stepwise and controllable fabrication procedure must be elucidated. Here, a series of structural transition of bismuth (Bi) adatoms, adsorbed on monolayer epitaxial graphene (MEG), is explored at room temperature. Bi adatoms undergo a structural transition from one-dimensional (1D) linear structures to two-dimensional (2D) triang...

abstract background: hyperthermia (also called thermal therapy or thermotherapy) is a type of cancer treatment in which body tissue is exposed to high temperatures (up to 113°f). research has shown that high temperatures can damage and kill cancer cells, usually with minimal injury to normal tissues.  for many years, biologists have investigated cancer by using monolayer cell culture. it is bec...

Static energy minimization and Monte Carlo simulation are used to study the effect of external electrostatic fields on the structure of a self−assembled monolayer (SAM) formed by methoxy tri(ethylene glycol) terminated alkanethiol molecules. It is found that fields of the order of 1 V/Å in strength can substantially change the equilibrium configuration of the SAM, making the oxygen atoms of the...

This paper describes a physical-organic study of the effect of uncharged, polar, functional groups on the rate of charge transport by tunneling across selfassembled monolayer (SAM)-based large-area junctions of the form AgS(CH2)nM(CH2)mT//Ga2O3/EGaIn. Here Ag is a template-stripped silver substrate, -Mand -T are “middle” and “terminal” functional groups, and EGaIn is eutectic gallium−indium all...

background: rad51 is a protein with critical role in double strand break repair. down-regulation of this protein has a significant effect in radiosensitivity of some cell lines like prostate carcinoma. compared to monolayer cell culture model, the spheroids are more resistant to radiation. the aim of the current study was to determine the rad51 protein level in du145 spheroids, and monolayer ce...

∗To whom correspondence should be addressed †Chemical Engineering Department, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands ‡Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands ¶Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford, Cambridge, Massachusetts, 02138, USA; and Kavli Ins...