نتایج جستجو برای: molecular marker polymorphism reelin gene

تعداد نتایج: 1746081  

Journal: :Neuroscience research 1997
H Yoneshima E Nagata M Matsumoto M Yamada K Nakajima T Miyata M Ogawa K Mikoshiba

We present yotari, a novel neurological mutant mouse whose mutation is transmitted in an autosomal recessive manner. The phenotype of yotari is very similar to that of reeler. yotari mutants are recognizable by their unstable gait and tremor and by their early deaths at around the time of weaning. The cerebella of homozygous yotari are hypoplastic and have no foliation. A molecular and a granul...

Introduction: Nephrotic syndrome (NS) is a genetic disease belonging to a heterogeneous group of glomerular disorders, which mainly occurs within the children. Linkage analysis using single nucleotide polymorphisms (SNP) is used as an indirect method in molecular diagnosis of the disease. A large number of SNP markers have been introduced in NPHS2gene in the available electronic databases. M...

آذرفام, پروین, حسین‌پور فیضی, محمدعلی, حلیمی, منیژه, رجحان ن‍ژاد, مهدیه, منتظری, وحید, پولادی, ناصر,

Introduction: Survivin gene, as an apoptosis inhibitor, plays an important role in development of breast cancer. The differential expression of survivin in cancer versus normal adult cells as well as an association between high expression of survivin and aggressive tumors has led to use of survivin as a molecular marker for diagnosis and prognosis of tumors. The underlying mechanism of survivin...

Journal: :Journal of pharmaceutical research international 2021

This article refers to viewing the role of molecular markers during analyzing genome plants and their importance in plant biotechnology. In recent years, we observed techniques programs for improving breeding preserving genetic resources has been observed, biochemical indicators which represent basic material through determining diversity between genotypes it is never affected by external surro...

Hedayatullah Roshanfekr jamal Fayazi Khalil Mirzade Maryam Khatibi,

Lactoferrin is a glycoprotein with molecular weight 80 kDa iron-binding bond, which is composed of 690 amino acids. In most mammalian body fluids such as sweat, semen, tears, and saliva and milk neutrophil granules there. bovine lactoferrin gene be associated with susceptibility/resistance to mastitis and even with some economically important production traits. This study was carried out to det...

Hedayatullah Roshanfekr jamal Fayazi Khalil Mirzade Maryam Khatibi,

Lactoferrin is a glycoprotein with molecular weight 80 kDa iron-binding bond, which is composed of 690 amino acids. In most mammalian body fluids such as sweat, semen, tears, and saliva and milk neutrophil granules there. bovine lactoferrin gene be associated with susceptibility/resistance to mastitis and even with some economically important production traits. This study was carried out to det...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1997
G D'Arcangelo K Nakajima T Miyata M Ogawa K Mikoshiba T Curran

The neurological mouse mutant strain reeler displays abnormal laminar organization of several brain structures as a consequence of a defect in cell migration during neurodevelopment. This phenotype is a result of the disruption of reelin, a gene encoding a protein that has several structural characteristics of extracellular matrix proteins. To understand the molecular basis of the action of Ree...

Journal: :journal of livestock science and technologies 2014
z. jafari s. r. miraei ashtiani m. sadeghi

prophet of pou1f1 (prop1) plays direct or indirect important roles in the morphogenesis of pituitary gonadotropes as well as lactotropes, somatotropes and caudomedial thyrotropes. it also controls the expression of growth hormone, prolactin and thyrotropin subunits through regulatory pit1 factor. these hormones have important influences on production traits in most animal species including the ...

Journal: :The Journal of biological chemistry 2014
Gum Hwa Lee Zinal Chhangawala Sventja von Daake Jeffrey N Savas John R Yates Davide Comoletti Gabriella D'Arcangelo

Reelin is an extracellular protein that controls many aspects of pre- and postnatal brain development and function. The molecular mechanisms that mediate postnatal activities of Reelin are not well understood. Here, we first set out to express and purify the full length Reelin protein and a biologically active central fragment. Second, we investigated in detail the signal transduction mechanism...

The identification of molecular markers linked to leaf curl virus (CLCuV) disease resistance in cotton has the potential to improve both the efficiency and the efficacy of selection in cotton breeding programs. Genetic analysis suggested that CLCuV resistance is controlled by a single dominant gene. In this study, an interspecific F2 population derived from a cross of Gossypium barbadense and G...

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