In the photosynthetic purple bacterium Rhodobacter (Rba.) sphaeroides, light is absorbed by membrane-bound light-harvesting (LH) proteins LH1 and LH2. LH1 directly surrounds the reaction center (RC) and, together with PufX, forms a dimeric (RC-LH1-PufX)2 protein complex. In LH2-deficient Rba. sphaeroides mutants, RC-LH1-PufX dimers aggregate into tubular vesicles with a radius of approximately ...

Human α-defensins are proteins of the innate immune system that suppress viral and bacterial infections by multiple mechanisms including membrane disruption. For viruses that lack envelopes, such as human adenovirus (HAdV), other, less well defined, mechanisms must be involved. A previous structural study on the interaction of an α-defensin, human α-defensin 5 (HD5), with HAdV led to a proposed...

Electron microscopy (EM) and electron tomography (ET) have found extensive applica‐ tion to probe structural and dynamic properties of macromolecular assemblies. As an im‐ portant complementary to X-ray and NMR in atomic structural determination, EM has reached a milestone resolution of 2.2Å, enough for understanding atomic interactions, in‐ terpreting mechanism of functions, and for structure-...

Stephen W. T. Price,1 Nicholas Zonias,1 Chris-Kriton Skylaris,1 Timothy I. Hyde,2 Bruce Ravel,3,* and Andrea E. Russell1,† 1School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, United Kingdom 2Johnson Matthey Technology Centre, Blounts Court, Sonning Common, Reading RG4 9NH, United Kingdom 3National Institute of Standards and Technology, 100 Bureau Drive MS 8520, Ga...

cooperative object manipulation control of rigid-flexible multi-body systems in space is studied in this paper. during such tasks, flexible members like solar panels may get vibrated that in turn may lead to some oscillatory disturbing forces on other subsystems, and consequently produces error in the motion of the end-effectors of the cooperative manipulating arms. therefore, to design and dev...