drug design is generally achieved through trial and error methods, which is a time and resource consuming process and novel methods are needed to improve it. mathematical modelling is one of the possible solutions to speed up this process. in this study, we have presented box-jenkins model, to predict the vasorelaxant activity (pec50) of a set of benzopyrane compounds. we used the hyperchem sof...

there are three major strategies to form neural network ensembles. the simplest one is the cross validation strategy in which all members are trained with the same training data. bagging and boosting strategies pro-duce perturbed sample from training data. this paper provides an ideal model based on two important factors: activation function and number of neurons in the hidden layer and based u...

the quantitative structure-property relationship (qspr) method is used to develop the correlation between structures of refrigerants (198 compounds) and their critical temperature. molecular descriptors calculated from structure alone were used to represent molecular structures. a subset of the calculated descriptors selected using a genetic algorithm (ga) was used in the qspr model development...

In the present study, a model of a large Lithium Polymer (Li-Po) battery for use in the simulation of Hybrid Electric Vehicles (HEVs) is developed. To attain this goal, an Equivalent Circuit (EC) consisting of a series resistor and two RC parallel networks is considered. The accuracy and the response time of the model for use in an HEV simulator are studied. The battery parameters identifica...

background: multiple severity scoring systems have been devised and evaluated in adult sepsis, but a simplified scoring model for pediatric sepsis has not yet been developed. this study aimed to develop and validate a new scoring model to stratify the severity of pediatric sepsis, thus assisting the treatment of sepsis in children. methods: data from 634 consecutive patients who presented with ...

soil moisture retention curve is one of the soil hydraulic prosperities which its direct measurement is time consuming and expensive. therefore, indirect methods such as developing pedotransfer functions have been used to predict this characteristic from soil readily available or easily measurable data. in this study, multiple linear regression method was used to develop point pedotransfer func...