In this paper, an efficient methodology to retargeting and reuse of embedded mixed-signal blocks is presented. Parametrized layout templates, accurate behavioral modeling of mixed-signal blocks, and appropriate mechanisms for tuning sized circuits to new sets of specs are its key components.

This paper presents the complete design methodology of a very low-voltage ∆Σ third-order modulator from highlevel specifications down to layout. Behavioral models taking into account cell non-idealities are developed and used to map performance specifications to lower levels. Emphasis has been made on eventual design reuse through design plans and layout templates in a layout-oriented circuit d...

H-ZSM-5 nano-zeolites were synthesized by hydrothermal method using tetrapropylammonium hydroxide (TPAOH) as a template in the presence of various TPABr concentrations. The effect of different TPABr/TPAOH molar ratios was studied on the catalytic performance of dehydration of methanol to dimethyl ether (DME) in a fixed bed reactor under the same operating conditions (T=300°C, P=1 atm, and WHSV=...

Direct Sanger sequencing of a diploid template containing a heterozygous insertion or deletion results in a difficult-to-interpret mixed trace formed by two allelic traces superimposed onto each other. Existing computational methods for deconvolution of such traces require knowledge of a reference sequence or the availability of both direct and reverse mixed sequences of the same template. We d...

Palliative care (PC) has proven benefits of a holistic inter-professional approach to increasing quality of life, reducing suffering, increasing communication between families, patients, and providers, and decreasing the healthcare cost of end-of-life care by reducing the amount of hospitalizations and re-hospitalizations (Rabow et al., 2013). Even with these benefits, patients remain under-ref...

Biological RNA is a uniform polymer in three senses: it uses nucleotides of a single chirality; it uses only ribose sugars and four nucleobases rather than a mixture of other sugars and bases; and it uses only 3'-5' bonds rather than a mixture of different bond types. We suppose that prebiotic chemistry would generate a diverse mixture of potential monomers, and that random polymerization would...

Spatial normalization reshapes an individual's brain to match the shape and size of a template image. This is a crucial step required for group-level statistical analyses. The most popular standard templates are derived from MRI scans of young adults. We introduce specialized templates that allow normalization algorithms to be applied to stroke-aged populations. First, we developed a CT templat...

OBJECTIVES Few interventions have been designed that provide standardised information to primary care clinicians about the diagnostic and treatment recommendations resulting from cancer multidisciplinary team (MDT) (tumour board) meetings. This study aimed to develop, implement and evaluate a standardised template for lung cancer MDTs to provide clinical information and treatment recommendation...

bone like hydroxyapatite (nhap) was synthesized via an in situ biomimetic process in presence of wheat starch. the effect of polymer concentration alteration on the final structure of nhap was investigated. formation of the nhap at room temperature was confirmed by x-ray diffraction (xrd) and fourier transform infrared spectroscopy (ft-ir). size and morphology of the nhap samples were character...