BACKGROUND Well-designed prospective studies of substance misuse in first-episode psychosis can improve our understanding of the risks associated with comorbid substance misuse and psychosis. AIMS To examine the potential effects of substance misuse on in-patient admission and remission and relapse of positive symptoms in first-episode psychosis. METHOD The study was a prospective 15-month ...

OBJECTIVES To quantify the relation between substance misuse and psychiatric illness in the UK general practice population in terms of (a) the relative risk of developing one condition given prior exposure to the other and (b) the proportion of cases of one condition attributable to exposure to the other. DESIGN Population based prospective observational study using the general practice resea...

background: direct thrombin inhibitors and factor xa inhibitors are gaining popularity as alternatives to warfarin for patients requiring anticoagulation. toxicity due to these medications is difficult to manage because overdose experience is very limited and there is no clear guidance on when or whether to use antidote in this setting. case presentation: a 50-year-old man with normal renal fun...

INTRODUCTION Posttraumatic stress disorder (PTSD) and alcohol misuse, which frequently co-occur among combat veterans, have been linked to emotion dysregulation. Emotion dysregulation may explain the link between PTSD and alcohol misuse, and this investigation tested emotion dysregulation as a mediator of that relationship. METHOD Correlations between PTSD symptoms and cluster symptoms, emoti...

OBJECTIVE Studies have shown a relationship between combat experiences and alcohol misuse in military personnel; it is not known if there are specific combat experiences that confer a greater risk. The current study examined the association of specific types of combat experiences with a positive screen for alcohol misuse. METHODS 1120 U.S. soldiers who were members of brigade combat infantry ...

Although use cases are a popular modeling approach for engineering functional requirements, they are often misused when it comes to engineering security requirements because requirements engineers unnecessarily specify security architectural mechanisms instead of security requirements. After discussing the relationships between misuse cases, security use cases, and security mechanisms, this col...

COMM 227A. Honors: Film Appreciation. 3 Credits. Open only to students in the Honors College. This class will focus on both contextual and close text analysis of masterworks as they have influenced film art and industry. Students in this course are expected to develop basic research, communication, viewing and critical thinking skills as they apply their knowledge to the analysis of the film ex...

Background. Prescription opioids are the most frequently misused class of prescription drug among young adults aged 18-25, yet trajectories of opioid misuse and escalation are understudied. We sought to model opioid misuse patterns and relationships between opioid misuse, sociodemographic factors, and other substance uses. Methods. Participants were 575 young adults age 16-25 who had misused op...