-Enhancement of CCNU cytotoxicity by misonidazole (MISO) was studied in three tumours and two normal tissues in the mouse. The 3 experimental tumours (SCCVII/St, EMT6 and KHT) showed very different sensitivities to CCNU alone, but MISO enhanced the cell killing in ech case. The effect was not always dose-modifying, so that the CCNU dose range for the greatest enhancement was different in each o...

Supplementary Figure 1 Annotated isoforms in human and mouse genomes. Supplementary Figure 2 Estimates of  using single‐end reads. Supplementary Figure 3 Steps of MISO statistical inference procedure Supplementary Figure 4 Evidence for exon size‐dependent qRT‐PCR bias. Supplementary Figure 5 MISO estimation for 52 alternative exons in breast cancer tissue. Supplementary Figure 6 mRNA‐Seq data...

-The hypoxic cell radiosensitizer desmethylmisonidazole (1-(2-nitroimidazol-1-yl)-2,3-propandiol; Ro 05-9963; DEMIS) was administered to 4 dogs at doses of 50 and 200 mg/kg by both oral and i.v. routes. The resulting plasma, cerebro spinal fluid and urinary concentrations were measured by HPLC analysis; various pharmacokinetic parameters were obtained and compared with similar data for the pare...

In this paper, the energy efficiency of multi-input single-output and orthogonal frequency division multiplexing (MISO-OFDM) communication systems with power and capacity constraints is investigated. By formulating the power allocation problem of MISO-OFDM communication systems, the minimum subchannel transmission power is analyzed with power and capacity constraints. Simulation results indicat...

In this study, an analytical formula for multipleinput single-output single frequency network gain (MISOSFNG) is investigated. To formulate the net MISO-SFNG, we derived the average signal to interference plus noise ratio (SINR) where the gain achieved by the distributed MISO diversity as a function of power imbalance is curve-fitted. Further, we analyzed the losses owing to self-interferences ...

HESSELTINE, C. W. (Northern Regional Research Laboratory, Peoria, Ill.), AND K. SHIBASAKI. Miso. III. Pure culture fermentation with Saccharomyces rouxii. Appl. Microbiol. 9:515-518. 1961.-Excellent miso has been prepared with soybean grits inoculated with a pure culture of Saccharomyces rouxii strain NRRL Y-2547. Pure culture inoculum of this osmophilic yeast was prepared by growing the cultur...

Recent studies in mouse tumor systems have indicated a potential therapeutic advantage in combining the radiosensitizer misonidazole (MISO) with cancer chemotherapy drugs. One agent the antitumor activity of which has been enhanced to a greater extent than its hematological or gastrointestinal toxicities is the nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1nitrosourea (CCNU). Recently, sensitize...

Cooked grains of ae rice cultivars are too hard and non-sticky due to the presence of long-chain amylopectin, and ae rice cultivars are therefore called ``super-hard rice'' and cannot be used as table rice. However, they are promising in terms of their bio-functionality such as preventing diabetes. Miso (soybean paste) is a yeast-fermented food, made from steamed soybeans, salt, and inoculated ...

Recent studies in mouse tumor systems have indicated a potential therapeutic advantage in combining the radiosensitizer misonidazole (MISO) with cancer chemotherapy drugs. One agent the antitumor activity of which has been enhanced to a greater extent than its hematological or gastrointestinal toxicities is the nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU). Recently, sensitiz...

As part of the day-ahead market clearing process, MISO solves one of the most challenging Security Constrained Unit Commitment (SCUC) models. This paper introduces several developments on MIP SCUC formulation that result in significant performance improvement. Numerical results based on MISO data are presented. Index Terms – Electricity market, mixed integer programming, security constrained un...