Milk thistle is a medicinal plant with anti-inflammatory, antioxidant properties and in the treatment of chronic liver diseases. The therapeutic this have been showed within Alzheimer’s malady, Parkinson’s illness, burns, osteoporosis, cholestasis, sepsis, hypercholesterolemia, diabetes. can be used to decrease side effects chemotherapy radiation therapy for various types cancer.

UNLABELLED Milk thistle extracts have been used as medicinal herbs in the treatment of liver cirrhosis, chronic hepatitis (liver inflammation), and gallbladder disorders. Treatment claims also include lowering cholesterol levels; reducing insulin resistance; reducing the growth of cancer cells in breast, cervical, and prostate gland cancers; and antiviral activity. Other reported uses of milk t...

Phytochemical-mediated modulation of P-glycoprotein (P-gp) and other drug transporters may underlie many herb-drug interactions. Serial serum concentration-time profiles of the P-gp substrate, digoxin, were used to determine whether supplementation with milk thistle or black cohosh modified P-gp activity in vivo. Sixteen healthy volunteers were randomly assigned to receive a standardized milk t...

Extracts of milk thistle have been recognized for centuries as "liver tonics" and are well-known to prevent or reverse hepatotoxicity of reactive drug metabolites or naturally occurring toxins. Milk thistle extracts are now under intense study in the experimental therapeutics of cancer for chemoprevention, treatment, and amelioration of chemotherapy side effects. Precision in nomenclature, howe...

green synthesis of nanoparticles, as fundamental building blocks of nanotechnology, has recently attracted considerable attention. silver nanoparticles have unique physiochemical, biological and environmental properties which make them useful in a wide range of applications. in the present paper we report our research results on biosynthesis of silver nanoparticles from silver precursor using m...

Silymarin, an extract of the seeds of Silybum marianum L. (milk thistle), is used for treatment of liver diseases. It contains several active flavonolignans; the major are silybin, which is a mixture of diastereomers A and B, and silychristin. Low bioavailability of silybin and silychristin is related to low water solubility of these compounds. In order to enhance the solubility, S. marianum dr...

Globally, the risk of colorectal cancer (CRC) as well as the incidence of mortality associated with CRC is increasing. Thus, it is imperative that we look at alternative approaches involving intake of non-toxic natural dietary/non-dietary agents, for the prevention of CRC. The ultimate goal of this approach is to reduce the incidence of pre-neoplastic adenomatous polyps and prevent their progre...

The objective of this study was to investigate the effects of diets containing different levels of milk thistle (0, 100 and 200 g/kg dry matter) and grains (barley and corn) with different rumen degradation rates on rumen bacteria and whole rumen microorganisms (WRM) of Khuzestan buffalo. The gas production (GP) technique, two steps digestion and specific bacteria culture medium methods were us...

in order to evaluate the effects of organic, biological and chemical fertilizers on yield and yield components of milk thistle (silybum marianum l.), an experiment was conducted at the research station of ferdowsi university of mashhad based on complete randomized block design with three replications and six treatments during year 2007. treatments included inoculated seeds with azotobacter, com...