background: migarine is the most common headache around the world including iran. in recent years, vitamin d deficiency has been shown to a global health problem. a few studies have been determined inverse association between serum levels of vitamin d with a headache. so, in this study, we investigated the effect of vitamin d supplementation on symptoms and c-reactive protein(crp) among patient...

abstract background: migraine is a primary headache disorder that affects the neurovascular system. recent studies have shown that migraine patients with general obesity have higher characteristics of migraine attacks compared with normal weight patients, but data on central obesity are scarce. this study was done to assess the relationship between central obesity and the characteristics of mig...

OBJECTIVES Allergic rhinitis (AR) is an IgE mediated disease which is released by activation of mast cells and basophils, and often leads to sinus headache. Histamine which is the key mediator in the pathogenesis of AR, also plays an important role in the pathogenesis of migraine with nitric oxide (NO). Aim of our study was to investigate the frequency of migraine in patients with AR. METHODO...

background: migraine and other recurrent headaches are considered a major public health concern. levetiracetam, a broad spectrum anti-epileptic have been used in migraine prophylaxis. objectives: assessment the efficacy of levetiracetam on migraine in comparison to sodium valproate. materials and methods: this randomized double blind clinical trial was performed on patients with migraine headac...

Introduction: Women have been reported to have a higher risk for migraine. The pathogenesis of migraine is known to be related to genetic risk factors such as the presence of common polymorphisms C677T (rs1801133) and A1298C (rs1801131) in the MTHFR gene. The aim of the study was to examine the role of these two MTHFR polymorphisms as risk factors for pediatric migraine and examine the gender-s...

background: migraine is a common neurovascular disorder with multifactorial and polygenic inheritance. the aim of this study was to investigate the association of a migraine without aura and ala379val polymorphism of lipoprotein-associated phospholipase a2 (lp-pla2) gene in the iranian population. methods: in this study, 103 migraine patients and 100 healthy controls were enrolled. dna samples ...

The aim of this study is to determine a possible relationship between prevalence, frequency, and severity of migraine and obesity. All pertinent data from the literature have been critically examined and reviewed in order to assess the possible relationship between obesity and migraine, in particular migraine frequency and disability in children, as well as in adult population studies. Prevalen...

Background: A wide range of preventive medications for migraine attacks, with varying efficacy is currently in use. Studies comparing the efficacies of these drugs would be of value in the proper treatment of the disease. The present study compared the frequency, duration and intensity of migraine attacks during and following treatment with cyproheptadine (4 mg, twice daily) or Blellergal (bell...