Plasminogen is a circulating zymogen of plasmin, a primary fibrinolytic enzyme1}.Plasminogen binding to fibrin and vascular and blood cells increases the local concentration of the zymogenand accelerates the activation of plasminogen by plasminogen activators2). We have previously isolated a novel fungal triprenyl phenol, designed staplabin, which enhances plasminogen binding to fibrin and cult...

An endophytic fungal strain isolated from the leaves of Gymnema sylvestre was identified as Pestalotiopsis microspora VJ1/VS1 based on nucleotide sequencing of internal transcribed spacer region (ITS 1-5.8S-ITS 2) of 18S rRNA gene (NCBI accession number KX213894). In this study, an efficient and ecofriendly approach has been reported for the synthesis of silver nanoparticles (AgNPs) using aqueo...

The diversity of Xylaria species associated with termite nests in northeast Thailand was investigated. Among the 14 taxa included this study, 11 and one variety were described as new, another two resemble existing taxa, X. escharoidea nigripes. newly are chaiyaphumensis, conica, fulvescens, ischnostroma, margaretae, minima, reinkingii var. microspora, siamensis, sihanonthii, subintraflava, thie...

A new α-pyrone derivative 1, along with four known congeners 2, 3, 4 and 5, were isolated from the solid-substrate fermentation medium of the endophytic fungus Pestalotiopsis microspore isolated from the branch of Taxus chinensis. Their structures and relative configurations were elucidated by extensive spectroscopic analysis. The cytotoxic activities of the isolated α-pyrone derivatives agains...

I. Ringworm fungi. This is a very large class, but we need refer only to the following types:(a) Microspora. (b) Trichophyta. (c) Achoria. (d) Epidermophyta. The microspora have small spores in mosaic arrangement, and are found in profusion on the hair surface. They are responsible for most of the scalp ringworm in this country, and are ,either conveyed by human infection (M. audouini-the large...

Members of the phylum Microspora are all obligate intracellular parasites. Little is known concerning metabolic pathways in these parasites, some of which pose serious problems in immunocompromised patients. We investigated polyamine metabolism in the systemic pathogen Enterocytozoon cuniculi using intact pre-emergent spores, and cell-free preparations. We found both polyamine synthetic and int...