نتایج جستجو برای: microgravity condition

تعداد نتایج: 317796  

2015
Ying Gao Shuai Li Dan Xu Junjun Wang Yeqing Sun

Radiation and microgravity exposure have been proven to induce abnormal apoptosis in microRNA (miRNA) and mRNA expression, but whether space conditions, including radiation and microgravity, activate miRNAs to regulate the apoptosis is undetermined. For that purpose, we investigated miRNome and mRNA expression in the ced-1 Caenorhabditis elegans mutant vs the wild-type, both of which underwent ...

Journal: :Journal of neurophysiology 2012
L Bringoux J Blouin T Coyle H Ruget L Mouchnino

Gravitational force level is well-known to influence arm motor control. Specifically, hyper- or microgravity environments drastically change pointing accuracy and kinematics, particularly during initial exposure. These modifications are thought to partly reflect impairment in arm position sense. Here we investigated whether applying normogravitational constraints at joint level during micrograv...

Journal: :TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C 1999

Journal: :American journal of physiology. Cell physiology 2005
Steven J Pardo Mamta J Patel Michelle C Sykes Manu O Platt Nolan L Boyd George P Sorescu Min Xu Jack J W A van Loon May D Wang Hanjoong Jo

Exposure to microgravity causes bone loss in humans, and the underlying mechanism is thought to be at least partially due to a decrease in bone formation by osteoblasts. In the present study, we examined the hypothesis that microgravity changes osteoblast gene expression profiles, resulting in bone loss. For this study, we developed an in vitro system that simulates microgravity using the Rando...

Journal: :Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale 2009

ژورنال: پژوهش در پزشکی 2018

Abstract Introduction: Physiology of reproduction is very complex and many factors influence on animal infertility.Today, researchers simulate weightlessness physiology  for investigation about  space biology. The best successful model for microgravity physiology simulation on the floor is in the rat hind-limb suspenion .The aim of this study is evaluation and comparision of  the effect of v...

2017
Yoon Jae Kim Ae Jin Jeong Myungjoon Kim Chiwon Lee Sang-Kyu Ye Sungwan Kim

BACKGROUND Gravity is omnipresent on Earth; however, humans in space, such as astronauts at the International Space Station, experience microgravity. Long-term exposure to microgravity is considered to elicit physiological changes, such as muscle atrophy, in the human body. In addition, certain types of cancer cells demonstrate inhibited proliferation under condition of time-averaged simulated ...

Journal: :TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B 1999

Journal: Nanomedicine Journal 2019

Objective (s): Gravity could affect some system features and perform directly as an organizing field factor. Recent investigations have examined the titanium dioxide nanoparticles (TiO2 NPs) in biomedical applications, mostly in the cancer treatment field. This study aimed to evaluate the effects of simulated microgravity combined with TiO2 NPs in MDA-MB-231 cells proliferation for the first tim...

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