BACKGROUND Available treatments for lymphatic filariasis (LF) are limited in their longterm clearance of microfilaria from the blood. The safety and efficacy of a single-dose triple-drug therapy of the antifilarial drugs diethylcarbamazine (DEC), ivermectin (IVM), and albendazole (ALB) for LF are unknown. METHODS We performed a pilot study to test the efficacy, safety, and pharmacokinetics of...

BACKGROUND & OBJECTIVES Wuchereria bancrofti has shown nocturnal periodicity in India and other endemic countries of the world except pacific regions where non-periodic or diurnal sub-periodic forms have been reported. Presence of sub-periodic form of W. bancrofti in Andaman and Nicobar Islands, India and a case report of sub- periodic form of W. bancrofti from Mysore, India provide basis for e...

Sharma P, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-222321 Description A 35-year-old woman presented to outpatients with a 1-week history of high-grade fever and generalised malaise. General and systemic examination was unremarkable. On evaluation, her complete haemogram was within normal limits; however peripheral smear revealed the presence of thread-like larval forms of filaria, belongi...

heartworm disease is caused by dirofilaria immitis in dogs and cats. dirofilariasis is clinically considered very important, because of its severe and life threatening disease in case of even light infection. cats are infected much less commonly, even in areas which present heavily infected dogs. after clinical examination blood samples were collected from 120 companion and stray adult cats in ...

Mass drug administration (MDA) programs have achieved remarkable success in limiting the pathology and transmission of the human parasitic infections onchocerciasis and lymphatic filariasis. The full implementation of MDA campaigns for filariasis elimination has been stymied by the unacceptable incidence of severe adverse events observed following drug treatment of a subset of individuals who h...

Dirofilariaimmitis, which is otherwise known as heartworm, is an important parasite in dogs and other carnivores. It lives in the right ventricle of the heart, the pulmonary artery and the posterior vena cava, and its microfilaria can be found in the peripheral circulation. This is the first report of Dirofilariaimmitis infection in stray dogs in Khuzestan, a province in South-Western Iran. Blo...

Filariasis is a major health problem in tropical countries, including India. The disease is endemic all over India, especially in Uttar Pradesh, Andhra Pradesh, Orissa, Bihar, Jharkhand, Tamil Nadu, Kerala, and Gujarat. A heavy parasitic load may appear in the blood, urine with chyle, and at times in scrotal aspirates. It is very unusual to find microfilaria in thyroid aspirate. Here, we presen...

Between 1989 and 1995, blood surveys were performed for Wuchereria bancrofti infection in several barracks of the Brazilian army in the metropolitan Recife region. For initial screening, 60 microliters of capillary blood were examined for microfilaria. All men who tested positive had microfilaria quantified by filtration of venous blood through a polycarbonate membrane. Of 23,773 men screened, ...