We have established a single cell irradiation system, which allows selected cells to be individually hit with defined number of heavy charged particles, using a collimated heavy-ion microbeam apparatus at JAERI-Takasaki. This system has been developed to study radiobiological processes in hit cells and bystander cells exposed to low dose and low dose-rate high-LET radiations, in ways that canno...

Studies have shown that x-rays delivered as arrays of parallel microplanar beams (microbeams), 25- to 90-microm thick and spaced 100-300 microm on-center, respectively, spare normal tissues including the central nervous system (CNS) and preferentially damage tumors. However, such thin microbeams can only be produced by synchrotron sources and have other practical limitations to clinical impleme...

This paper investigates the development of a novel framework and its implementation for the nonlinear tuning of nano/microresonators. Using geometrically exact mechanical formulations, a nonlinear model is obtained that governs the transverse and longitudinal dynamics of multilayer microbeams, and also takes into account rotary inertia effects. The partial differential equations of motion are d...

Abstract The size dependent static pull-in instability of functionally graded (FG) microbeams in micro-electromechanical systems (MEMS) is studied, considering the influence axial force. material properties are varied beam thickness by a power-law function, and they calculated rule mixture. To account for microsize effect, classical Euler-Bernoulli theory employed combination with modified coup...

The resonant frequencies of released microcantilevers, microbeams, and microplates are among the most important response characteristics for microelectromechanical systems such as resonators, sensors, and radio frequency (RF) switches. It is generally believed that the resonance frequencies of such structures decrease monotonically as the surrounding gas pressure is increased from vacuum condit...

The objective of this paper is to demonstrate the integration of a MOF thin film on electrostatically actuated microstructures to realize a switch triggered by gas and a sensing algorithm based on amplitude tracking. The devices are based on the nonlinear response of micromachined clamped-clamped beams. The microbeams are coated with a metal-organic framework (MOF), namely HKUST-1, to achieve h...