A multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. For this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 M HCl containing NaCl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...

Objective: The main objective of the present work is development polymeric low-density microballoons for prolonged gastroretentive delivery and optimization promising formulation by central composite design response surface methodology. Methods: Mebendazole-loaded were prepared emulsion solvent diffusion method using Eudragit S-100 hydroxypropyl methylcellulose as release controlling polymers. ...

a multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. for this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 m hcl containing nacl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...

In this paper, a fundamental understanding of the densification mechanics polymeric syntactic foams under compressive loading is established. These are closed cell composite with thin-walled microballoons dispersed in matrix (resin) whose structure provides excellent mechanical properties, like high strength and low density. There several parameters that can contribute towards their including, ...

Many laser fusion target designs call for metal pusher layers which have surface roughnesses of less than 50 nm and thickness uniformities of a few percent. Applying coatings which meet these requirements to spherical glass microballoons is a unique challenge. One reason for this is the problem which arises when the coating material isdeposited on a surface at oblique angles of incidence, as it...