Diabetes is a metabolic disease which damage blood vessel. Damage in retinal blood vessel of the human eye due to effect of diabetes is termed as Diabetic Retinopathy (DR). This abnormality in the blood vessel will cause a leakage of blood from the vessel and forms a red dot. This is named as Microaneurysm. Microaneurysm in the retina causes a swelling of retinal tissue which in turn causes clo...

Retinal microaneurysms are the earliest clinical sign of diabetic retinopathy disease. Detection of microaneurysms is crucial for the early diagnosis of diabetic retinopathy and prevention of blindness. In this paper, a novel and reliable method for automatic detection of microaneurysms in retinal images is proposed. In the first stage of the proposed method, several preliminary microaneurysm c...

PURPOSE Subthreshold laser treatment of diabetic macular edema (DME) may have less deleterious effects on the photoreceptors than regular continuous wave laser. This study aimed to assess whether subthreshold laser causes a long-term damage to the retinal structures, as demonstrated by spectral-domain optical coherence tomography (SD-OCT), and to evaluate the change in the axial diameter of ret...

AIM To investigate the contribution of fluorescein angiographic leaking microaneurysms (leak-MA) versus non-leaking microaneurysms (non-leak-MA) to retinal thickening in diabetic retinopathy. METHODS A consecutive series of 38 eyes from 24 patients with diabetic retinopathy was included. Leak-MA and non-leak-MA in each eye were selected in pairs at corresponding topographic location. Leaking ...

Intravitreal anti-vascular endothelial growth factor (VEGF) agents can treat macular edema (ME) in branch retinal vein occlusion (BRVO). However, refractory ME, the mechanism of which is not well elucidated, occurs frequently. Sixty-six eyes with ME secondary to BRVO were enrolled in this retrospective observational case-control study. Twenty eyes received a sub-Tenon's capsule injection of tri...

The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities to be studied in detail without disturbing the tissue architecture. Only one m...

Diabetic retinopathy is the leading cause of blindness in the western working age population and microaneurysms are one of the first pathologies associated with diabetic retinopathy. We have developed a prototype microaneurysm detection system for non-mydriatic colour fundus images. Candidate microaneurysms are located by a standard method that enhances small round features after background int...

Diabetic retinopathy is characterized by the development of retinal microaneurysms. The damage can be prevented if disease is treated in its early stages. In this paper, we are comparing Support Vector Machine (SVM) and Naïve Bayes (NB) classifiers for automatic microaneurysm detection in images acquired through non-dilated pupils. The Nearest Neighbor classifier is used as a baseline for compa...

Diabetic retinopathy is one of the main causes vision loss, and it can be identified through ophthalmological examinations that aim to locate presence retinal lesions such as Microaneurysms, Hemorrhages, Soft Exudates, Hard Exudates. The development computerized approaches perform instance segmentation these help in early diagnosis disease. However, instances artifacts retina a complex task due...