نتایج جستجو برای: micro rna

تعداد نتایج: 363773  

2009
H. Alexander Ebhardt Herbert H. Tsang Denny C. Dai Yifeng Liu Babak Bostan Richard P. Fahlman

Recent advances in DNA-sequencing technology have made it possible to obtain large datasets of small RNA sequences. Here we demonstrate that not all non-perfectly matched small RNA sequences are simple technological sequencing errors, but many hold valuable biological information. Analysis of three small RNA datasets originating from Oryza sativa and Arabidopsis thaliana small RNA-sequencing pr...

2015
Christine How Melania Pintilie Jeff P. Bruce Angela B. Y. Hui Blaise A. Clarke Philip Wong Shaoming Yin Rui Yan Daryl Waggott Paul C. Boutros Anthony Fyles David W. Hedley Richard P. Hill Michael Milosevic Fei-Fei Liu

Cervical cancer remains the third most frequently diagnosed and fourth leading cause of cancer death in women worldwide. We sought to develop a micro-RNA signature that was prognostic for disease-free survival, which could potentially allow tailoring of treatment for cervical cancer patients. A candidate prognostic 9-micro-RNA signature set was identified in the training set of 79 frozen specim...

Journal: :Molecular cell 2015
Jenna L Jewell Fabian Flores Kun-Liang Guan

In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.

2015
Shunmugiah V Ramesh Milind B Ratnaparkhe Syed M Husain Virender S Bhatia

In an era of small RNA (sRNA) transcriptomics, microRNAs (miRNAs) require little introduction. miRNAs are small non-coding RNAs (sncRNAs) that play vital role in post transcriptional gene silencing (PTGS) in nucleotide sequence dependent manner either by cleaving target mRNA or by repressing cognate mRNA translation [1]. In plants, miRNAs have been implicated in regulating the expression of tar...

Journal: :Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2009
Jacques Demongeot Emmanuel Drouet Adrien Elena Andrès Moreira Yassine Rechoum Sylvain Sené

For comparing RNA rings or hairpins with reference or random ring sequences, circular versions of distances and distributions like those of Hamming and Gumbel are needed. We define these circular versions and we apply these new tools to the comparison of RNA relics (such as micro-RNAs and tRNAs) with viral genomes that have coevolved with them. Then we show how robust are the regulation network...

Journal: :Microbiology 2003
Robert A Cox

In order to further understand the different physiological states of the tubercle bacillus, a frame of reference was sought by first correlating the macromolecular compositions of Escherichia coli with specific growth rates and also with the rates of protein synthesis. Data for DNA : protein : RNA were converted to the average amounts of DNA [m(DNA(av))], protein [m(p(av))] and RNA [m(RNA(av))]...

ژورنال: :genetics in the 3rd millennium 0
حسین محمدی hossein mohammadi دانشجوی ارشد ژنتیک و اصلاح نژاد، پردیس کشاورزی و منابع طبیعی، دانشکده علوم و مهندسی کشاورزی، دانشگاه تهران محمد مرادی شهر بابک mohammad moradi shahrbabak مصطفی صادقی mostafa sadeghi حسین مرادی شهر بابک hosein moradi shahrbabak حمید رضا قدیمی hamidreza ghadimi

برای 50 سال واژه ژن مترادف با مناطقی از ژنوم بود که توسط mrnas رمزگذاری و به پروتئین ترجمه می شدند. با این حال ، مطالعات گسترده اخیر ژنوم نشان داده است که در ژنوم انسان رونویسی و تولیدات بوسیله هزاران rnaهای غیر کد شونده تنظیم گر انجام می شود که شامل micro rna ، small nucleolar rna ، و small interfering rnaمی باشند که از جمله مولکول های کارکردی هستند که در گروه rnaهای غیر کد شونده کوچک قرار می ...

Abolghasem Ajami, Alireza Rafiei, Eshrat Gharaee, Fatemeh Rahbarizadeh, Mohammad bagher Hashemi Sooteh, Mohammad Soltany-Rezaee-Rad, Negar Mottaghi-Dastjerdi, Saeid Abediankenari,

Background: RNAi (RNA interference) is a new strategy in gene therapy and biotechnology which provides new promises in the treatment of different diseases such as cancer and viral diseases. CCND1 which is a key gene in cell cycle is amplified and over expressed in esophageal cancer. The objective of this study was production and siRNAs for CCND1, the key gene in cell cycle. Materials and Metho...

Journal: :EMBO Molecular Medicine 2018

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید