BACKGROUND Recent studies suggest that uric acid is a mediator of diabetic nephropathy. We hypothesized that elevated serum uric acid levels are a strong predictor of albuminuria in patients with type 1 diabetes. METHODS We analyzed data from the Coronary Artery Calcification in Type 1 Diabetes study, a prospective observational study. A stepwise logistic regression model was applied to predi...

| June 2014 | 581 HbA1c concentration in male interventional group is signifi cantly less than that of the control group.[7] We concluded that weekly vitamin D supplementation had benefi cial eff ects on glycemic parameters in male T2DM patients.[6] Study regarding the glycemic control of vitamin D revealed diff erent results. Recently, in a study conducted by Huang et al., the diff erence in v...

results the prevalence of micro and macroalbuminuria was 17.2% and 17.6%, respectively. microalbuminuria was significantly associated with longer diabetes duration, increased fasting plasma glucose, and diastolic blood pressure. it was also found that higher plasma glucose and bun (blood urea nitrogen) were risk factors for macroalbuminuria. conclusions prevalence of both micro- and macroalbumi...

Background: Diabetic nephropathy is a common complication of diabetes mellitus type2. The neutrophil gelatinase Associated lippocallin (NGAL) is an ubiquitous protein consist of 178 amino acid. NGAL can be identified in plasma and urine starting 24 hours after a kidney injury resulting changes in glomerular filtration and tubular reabsorption and with increased secretion in tubular epithelial c...

OBJECTIVE To analyze the longitudinal data of multiple patients and to discover new temporal knowledge, we designed and developed the Visual Temporal Analysis Laboratory (ViTA-Lab). In this study, we demonstrate several of the capabilities of the ViTA-Lab framework through the exploration of renal-damage risk factors in patients with diabetes type II. MATERIALS AND METHODS The ViTA-Lab framew...

BACKGROUND The aim of this study was to evaluate whether global levels of DNA methylation status were associated with albuminuria and progression of diabetic nephropathy in a case-control study of 123 patients with type 2 diabetes- 53 patients with albuminuria and 70 patients without albuminuria. METHODS The 5-methyl cytosine content was assessed by reverse phase high pressure liquid chromato...

INTRODUCTION Microalbuminuria is an early sign of kidney damage. The prevalence of microalbuminuria in Singapore has been reported to be 36.0%-48.5%. However, the prevalence of microalbuminuria reported in these studies was determined with one urine sample using a qualitative urine test. The aim of this study was to determine the prevalence of micro- and macroalbuminuria using a more stringent ...

INTRODUCTION Micro-albuminuria is considered an early marker of glomerular injury in patients with diabetes but it has yet to be determined whether testing for markers of tubular injury can also identify people who are at risk of progressive renal disease. OBJECTIVE To evaluate markers of tubular injury and renal characteristics in a sample of community treated type 2 diabetic subjects. MAT...

Micro- or macroalbuminuria is associated with increased cardiovascular risk factors among patients with type 2 diabetes, but whether albuminuria within the normal range predicts long-term cardiovascular risk is unknown. We evaluated the relationships between albuminuria and cardiovascular events in 1208 hypertensive, normoalbuminuric patients with type 2 diabetes from the BErgamo NEphrologic Di...

BACKGROUND Failure of diagnosing and treatment of albuminuria play a role in morbidity and mortality in type 2 diabetes (T2DM). We evaluated guideline adherence and factors associated with albuminuria screening and treatment in T2DM patients in primary care. METHODS Guidelines recommend annual measurement of albuminuria and, if increased, treatment with renin-angiotensin-aldosterone system (R...