background: angiogenesis, which is required for embryonic development and many physiological events, plays crucial role in many pathological conditions such as tumor growth and metastasis. recent studies indicate anticancer and antitumor properties of saffron against human cancers. many processes are affected by electromagnetic field (emf) and its effect on proliferation and gene expression wer...

objective(s): chemoresistance remains the main causes of treatment failure and mortality in cancer patients. there is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. induction of drug efflux due to overexpression of                  p-glycoproteins is considered as an important leading cause of multidrug resis...

Abdo J. Najy, Gregory Dyson, Bhanu P. Jena, Chen-Yong Lin, and Hyeong-Reh C. Kim Department of Pathology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan; Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan; Department of Physiology, Wayne State University School of Medici...

BACKGROUND Among cancers that affect both men and women, colorectal cancer is one of the leading causes of cancer-related death in Michigan. The American Cancer Society estimates 4,730 new cases and 1,700 deaths due to colorectal cancer in Michigan for 2013. Screening can detect colorectal cancer earlier, when treatment is more successful. COMMUNITY CONTEXT The Michigan Department of Communit...

Departments of Molecular and Cellular Oncology, Cancer Biology, Pathology, Molecular Pathology, Hematopathology, Breast Medical Oncology, and Imaging Physics, the University of Texas, M. D. Anderson Cancer Center, Houston, Texas; Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and Comprehensive Cancer Cent...

it has been reported that several conifers possess cytotoxic activities on some human tumor cell lines. taxol as a natural cytotoxic compound has been extracted from this family. in a program to screen the cytotoxic effects of natural resources, male and female branchlets, fruit or bark of two different species of iranian conifers were collected, identified and the cytotoxic effects of their hy...

cancer screening and treatment decisions Scott R. Hawken*, Gregory B. Auffenberg*, David C. Miller*, Brian R. Lane, Michael L. Cher, Firas Abdollah, Hyunsoon Cho and Khurshid R. Ghani* for the Michigan Urological Surgery Improvement Collaborative *Department of Urology, University of Michigan, Ann Arbor, Section of Urology, Spectrum Health Medical Group, College of Human Medicine, Michigan Stat...

Abstract: Plants produce a variety of secondary metabolites, one which is essential oils that contain volatile compounds and are useful for humans. Cymbopogon nardus contains can inhibit the proliferation cancer cells. This research aims to explore antiproliferation activity C.nardus’ with different concentrations against breast Michigan Cancer Foundation-7 (MCF-7) Antiproliferation test was ca...

1 Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA 2 Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA 3 Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA 4 Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI...

Departments of Radiation Oncology, *DeCesaris Cancer Institute, Anne Arundel Medical Center, Annapolis, Maryland, yHenry Ford Health Systems, Detroit, Michigan, zMayo Clinic, Rochester, Minnesota, xWashington University in St. Louis School of Medicine, St. Louis, Missouri, kKarmanos Cancer Center, Detroit Medical Center, Detroit, Michigan, {University of North Carolina Lineberger Comprehensive ...