Nicotine at the dose level of 0.3 mg/100 g body weight was administered to normal cycling mice for 15 days through oral and intraperitoneal routes. At autopsy on 16th day significant reduction in the ovarian and uterine weight was observed. Histological observations showed decrease in the number and size of Graafian follicles, corpora lutea and increase in the atretic follicles in the ovary. Th...

background: aging contains morphological and functional deterioration in biological systems. d-galactose (d-gal) generates free radicals and accelerates aging. portulaca oleracea (purslane) may have protective effect against oxidative stress. objective: purslane ethanolic extract effects were evaluated on antioxidant indices and sex hormone in d-gal aging female mice. materials and methods: 48 ...

Endometriosis is a gynecological disease defined by the growth of endometrium outside of the uterus. Although endometriosis contributes to 50% of female infertility cases, medical treatments are incompatible with pregnancy. Angiogenesis, the growth of blood vessels from existing vasculature, plays a crucial role in endometriotic lesion growth and survival. Previously, we demonstrated the effect...

Endometriosis is a benign proliferative lesion in which ectopic endometrium or endometrium-like tissue is observed, and is roughly divided, according to the site of development, into internal endometriosis occurring in the uterus and external endometriosis occurring outside the uterus. Cases of endometriosis in the inguinal region are uncommon, accounting only for 0.8% of all cases of external ...

introduction: stem cell biology has been the subject of much recent discussion. embryonic stem (es) cells, derived from the inner cell mass of the blastocyst stage of early mammalian embryos are expected to become a powerful tool in future regenerative medicine and developmental biology due to their capacity of self-renewal and pluripotency. in the present study, the ultrastructural development...

During gestation, many important molecular factors associated with embryo implantation and development occur within the female reproductive tract. The endometrium includes the muscosal lining of the uterus, which gives a convenient location for implantation and development of a fertilized egg and fetus. At present, the molecular cascades in the uterus endometrium during pregnancy periods in far...

objective: the aim of this study was to evaluate and compare the population of natural killer t lymphocyte (nkt) in the uterus and spleen of the hyperstimulated and control mice at the seventh day of pregnancy. materials and methods: the superovulated and control mice were put individually in a cage with a male mouse. in the next morning they were considered for observing the vaginal plag. the...

Abstract Xylene is one of the environmental pollutants with a negative impact mainly on several organ systems. The aim this study was to determine effect xylene uterus mice. performed 12 adult female Control mice (n = 6) were fed shredded pellets at dose 4 g per day. same diet and orally administered 10 μl day for 14 days. synchronized using Whit-ten introduced males before end procedure. Mice ...

Slight differences in structure fundamentally change the effects, which can be corticoid, androgen, progestagen or estrogen. The latter 3 are called sex steroid hormones. Each type of sex steroid hormone is composed of a group of molecules, with slightly different effects. Sex steroid hormones are secreted by the ovary and by the adrenal gland. Oestrogens are the typical female hormone which wi...

Endometrial cancer Double uterus Histopathology Abstract We report a rare case of endometrial carcinoma arisen from both horns of an asymmetrical double uterus. Dr. Yoshiharu Tsukahara, Department of Obstetrics and Gynecology, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto 390 (Japan) Introduction Although the incidence of a malformed uterus is not so rare, there have been few re...