There is considerable experimental evidence in support of the view that, in solution, the state of molecular dispersion of insulin is dependent on the net charge of the protein (10, 6, 8). In these investigations, alterations of the net positive charge were obtained by varying the pH of the solutions, with due consideration of the effect of the specific binding affinity of the protein for anion...

two modified methods for assaying sodium diclofenac were developed by gc and hplc. diclofenac was converted into methyl ester derivative by methyl iodide in acetone. the ester was extract and subjected to glc with flame ionization detector. %5 se-30/chrom w-hp (80-100 mesh) was used as a column in gc. for reversed phase hplc, the mobile phase was methanol and water (55-45). the separation was p...

Seven new azalomycin F analogs (1-7) were isolated from the broth of mangrove Streptomyces sp. 211726, and respectively identified as 25-malonyl demalonylazalomycin F5a monoester (1), 23-valine demalonylazalomycin F5a ester (2), 23-(6-methyl)heptanoic acid demalonylazalomycins F3a ester (3), F4a ester (4) and F5a ester (5), 23-(9-methyl)decanoic acid demalonylazalomycin F4a ester (6) and 23-(10...

diesel fuel has a limited resource and concerns over environmental pollution areleading to the use of ‘bio-origin fuels’ as they are renewable and environmentally benign. jatrophamethyl ester, an esterified biofuel, has an excellent cetane number and a reasonable calorific value.it closely resembles the behaviour of diesel. however, being a fuel of different origin, the standarddesign limits of...

Laboratory studies were conducted using C-aminocyclopyrachlor (DPX-MAT28) and its C-methyl ester formulation (DPX-KJM44) to (1) determine the adjuvants’ effects on absorption, (2) compare the absorption and translocation of aminocyclopyrachlor free acid with the methyl ester, and (3) determine the rate at which aminocyclopyrachlor-methyl ester is metabolized to the free acid in Canada thistle. ...

The extraction of yacon [Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson; Asteraceae] leaves and chromatographic separation yielded two new antibacterial melampolide-type sesquiterpene lactones, 8beta-tigloyloxymelampolid-14-oic acid methyl ester and 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, as well as the four known melampolides, sonchifolin, uvedalin, enhydrin and fluc...

chyuri (Diploknema butyracea (roxburgh) H. J. lam) is widely used in nepal for its medicinal properties and as a source of chyuri ghee (fat) extracted from the seeds. the main purpose of the present study was the gc-MS analysis of fatty acids in seed fat of chyuri after acidic methanolysis. Palmitic acid methyl ester (1), linoleic acid methyl ester (2), oleic acid methyl ester (3) and steric ac...

Two new triterpenoid glycosides were isolated (one of them as the methyl ester) as major components from leaves of Ilex chinensis Sims (Aquifoliaceae) . The structures of these glycosides, termed ilexoside A (1) and ilexoside B methyl ester (2a), have been established to be 3ƒÀ-ƒ-(ƒÀ-Dxylopyranosyl)siaresinolic acid and 3ƒÀ-ƒ-(ƒÀ-D-xylopyranosyl)pomolic acid methyl ester , respectively, based o...

The amide-linked local anesthetics can be used safely in patients susceptible to malignant hyperthermia (MH). 4-Hydroxybenzoic acid methyl ester contained as a preservative in local anesthetic solution was suspected to have triggered MH in a patient who had received nerve block with lidocaine solution. The author investigated the effects of 4-hydroxybenzoic acid methyl ester on Ca(2+)-related f...