background: addiction to narcotics ‎can cause serious problems and ‎monetary losses. therapeutic ‎success can be predicted ‎through identifying lapse risk ‎factors.‎ objective: determining job risk ‎factor of lapse.‎ methods: this was a cross ‎sectional study on 351 addicts ‎visiting five methadone clinics. a ‎data collection sheet consisting ‎of questions on demographic ‎and job information wa...

Methadone maintenance therapy for the treatment of opioid dependence continues to carry a social stigma. Until recently, patients on methadone were not considered for liver transplantation. We describe the first case of a patient on methadone who received a liver transplant for end stage liver disease and was successfully treated for recurrent hepatitis C. More than five years post transplant a...

Effects of Methadone on Olfactory Memory Span Melissa Deal In 2008, an estimated 268,000 individuals received methadone in certified opioid treatment programs in the United States in an effort to effectively treat an opiate addiction (Substance Abuse and Mental Health Services Administration, 2010). Because of its high rate of use, a major concern regarding methadone maintenance is the possibil...

background: the role of methadone in qtc prolongation, torsades de pointes (tdp) arrhythmia and sudden cardiac death has been debated. because of widespread use of methadone in methadone maintenance treatment (mmt) centers, we aimed to study dose-related effects of methadone on qtc prolongation. methods: in a comparative observational study, 90 patients who were under mmt were evaluated. patien...

the ministry of health, treatment and medical education of iran has recently announced an estimated figure of 200,000 injecting drug users (idus). the aim of this study was to pilot a national program using demographics, types of drug abuse and prevalence of blood-borne infections among idus.in order to elicit data on demographics, types of drug abuse and prevalence of blood-borne infections am...

background and aims: sexual dysfunction is a common complaint among drug abusers in the treatment with methadone and buprenorphine. the aim of this study was to assess sexual dysfunction in patients undergoing methadone or buprenorphine for maintenance therapy. methods: this research was a cross-sectional study. a 3-parts questionnaire (demographic questions, international index of erectile fun...

background: one of the major challenges in current methadone maintenance treatment retention rates in the treatment and prevention of relapse addiction. the aim of this study was determine the factors influencing relapse based on health belief model. methods: a cross-sectional study was conducted among 384 patients on methadone maintenance treatment referred to addiction clinic in hamadan, whic...

background opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as hiv and hepatitis b and c and improve the quality of life in opioid-dependent patients. objectives the aim of this study was to assess the anthropometric and socio-d...

Dr. Eamon Keenan The previous speaker has given a reasoned a balanced argument in favour of the use of methadone as an effective intervention in the treatment of opiate dependence syndrome. One interesting point to emerge and one that highlights the emotive nature of methadone treatment, is his justification of methadone maintenance on utilitarian moral grounds. That a medicinal product, with p...