Hyperglycemia (Glucose> 250 mg/dL), metabolic acidosis (pH

Objective We planned a cross-sectional analysis to determine the frequency and severity of metabolic acidosis in patients taking topiramate while awaiting craniotomy. Methods Eighty patients (18 - 65 years) taking topiramate to control seizures while awaiting elective craniotomy were enrolled. Any signs of metabolic acidosis or topiramate-related side effects were investigated. Blood chemistry ...

In very rare cases severe metabolic acidosis may cause hypotension, respiratory depression and cardiac arrest. Although rare this cause of shock is important because correction of the metabolic acidosis may be life-saving. Mild metabolic acidosis is relatively common in cases of hypoxia and shock, and is an index of the severity of these. Recurrent metabolic acidosis, which reflects failure of ...

1. Whole-body intracellular pH (pHi) was measured by the 14C-labelled DMO method in twenty-four control subjects, eighteen normal subjects with induced acute metabolic alkalosis, ten normal subjects with induced acute metabolic acidosis, twelve normal subjects with chronic acidosis and in fifteen patients with chronic renal insufficiency and acidosis. 2. The change in pHi per unit change in ext...

Clinically, a decrease in blood pH may be due to either a reduction in bicarbonate concentration ([H[Formula: see text]], metabolic acidosis) or an increase in[Formula: see text] (respiratory acidosis). In mammals, metabolic acidosis induces a far greater increase in urine calcium excretion than respiratory acidosis. In cultured bone, metabolic acidosis induces a marked increase in calcium effl...

BACKGROUND Clinical features of metabolic acidosis and pneumonia frequently overlap in young diarrheal children, resulting in differentiation from each other very difficult. However, there is no published data on the predictors of metabolic acidosis in diarrheal children also having pneumonia. Our objective was to evaluate clinical predictors of metabolic acidosis in under-five diarrheal childr...

1. Effective renal plasma flow, glomerular filtration rate and cardiac output were measured in osmotically loaded dogs before and during comparable acute respiratory and metabolic acidosis. 2. Urine output increased in control dogs and in animals with metabolic acidosis, but declined with respiratory acidosis. Effective renal plasma flow and glomerular filtration rate declined with respiratory ...

A 52 year old female patient presented to emergency casualty with Acute onset quadriparesis respiratory muscle involvement in. During initial work up Serum electrolytes showed severe hypokalemia. Arterial blood gas normal anionic gap metabolic acidosis positive urine anion and examination alkaline PH in the presence of systemic acidosis. All these findings suggest Distal Tubular Acidosis. Furth...

Thirty four infants were studied; 21 with acute gastroenteritis, dehydration, and metabolic acidosis and 13 who served as controls. All infants with metabolic acidosis and without neurological signs had a normal to near normal cerebrospinal fluid acid base balance, but five with metabolic acidosis and severe neurological signs had cerebrospinal fluid acid base disequilibrium. Acute metabolic ac...