We present a multi-scale generative model for EEG, that entails a minimum number of assumptions about evoked brain responses, namely: (1) bioelectric activity is generated by a set of distributed sources, (2) the dynamics of these sources can be modelled as random fluctuations about a small number of mesostates, (3) mesostates evolve in a temporal structured way and are functionally connected (...

The present paper offers a meso-scale numerical model to investigate the effects of random distribution of aggregate particles and steel fibers on the elastic modulus of Steel Fiber Reinforced Concrete (SFRC). Meso-scale model distinctively models coarse aggregate, cementitious mortar, and Interfacial Transition Zone (ITZ) between aggregate, mortar, and steel fibers with their respective materi...

The oxidation of heme to biliverdin IXalpha by heme oxygenase involves regiospecific alpha-meso-hydroxylation followed by extrusion of the alpha-meso-carbon as CO. In an earlier study, enzymatic oxidation of the four meso-methylmesoheme isomers suggested that the reaction regiospecificity is sensitive to the electronic properties of the meso-methyl group (Torpey, J. W., and Ortiz de Montellano,...

The tumor microenvironment is crucial to the progression of various malignancies. Malignant pleural mesothelioma (MPM), which originates from the pleura, grows aggressively in the thoracic cavity. Here we describe an orthotopic implantation SCID mouse model of MPM and demonstrate that α-SMA-positive fibroblast-like cells accumulate in the tumors produced by the human MPM cell lines MSTO-211H an...

the present paper offers a meso-scale numerical model to investigate the effects of random distribution of aggregate particles and steel fibers on the elastic modulus of steel fiber reinforced concrete (sfrc). meso-scale model distinctively models coarse aggregate, cementitious mortar, and interfacial transition zone (itz) between aggregate, mortar, and steel fibers with their respective materi...

Enantioselective desymmetrization of meso-aziridines and meso-epoxides with various nucleophiles by organocatalysis has emerged as a cutting-edge approach in recent years. This review summarizes the origin and recent developments of enantioselective desymmetrization of meso-aziridines and meso-epoxides in the presence of organocatalysts.

Growing numbers of promising visions of the future and scenarios that may lead toward building sustainable societies are being developed. At the same time, advanced technologies and research seeds that could increase the likelihood of achieving such visions are also being rigorously conceived. Even so, we face challenges and barriers in achieving these visions due to large gaps between individu...

The atypical two-electron oxidation of thioanisole and its p-methyl, p-methoxy, and p-nitro analogues by horseradish peroxidase, contrary to earlier reports, stereoselectively produces the (8) sulfoxides in 6070% enantiomeric excess. Horseradish peroxidase reconstituted with 6-meso-ethylheme has little peroxidase (guaiacol oxidizing) activity, as previously reported, but exhibits increased sulf...