The condensation of a carboxylic acid with alcohols, amides, and mercaptans under physiological conditions usually requires an external source of energy. In most systems the external source has been shown to reside in the apparent hydrolysis of adenosine triphosphate (ATP), but the detailed way in which the energy is made available for the condensation is obscure. In the action of glutamine syn...

Binuclear Fe-complexes that are readily prepared by treating Bu(4)N[Fe(CO)(3)(NO)] with an excess of thiol or from Fe-salts under reductive conditions are potent catalysts for the regioselective allylic sulfenylation. Low catalyst loadings of only 0.25 mol% and reaction temperatures of only 40 °C allow for the coupling of functionalized allylic starting materials with functionalized mercaptans ...

Determination and location of cystine residues are essential to protein characterization since their disulfide bonds stabilize chainfolding and multichain structure responsible for physical and biological properties. Reduction with mercaptans, such as dithiothreitol, in dissociating solvents is the choice procedure for attaining disulfide cleavage, since other methods may cause undesirable side...

It has been suggested that mercaptans are important factors in the pathogenesis of hepatic encephalopathy. Using a gas liquid chromatographic technique which uses propanethiol as internal standard and a sulphur specific detector, blood methanethiol concentration was found to be significantly risen in encephalopathic patients with liver disease (13.2±1.0 nmol/ml; n=47) compared with control subj...

The effect of four mercapto flavor compounds (1,2-ethanedithiol, 1-butanethiol, 2-methyl-3-furanthiol, and 2-furanmethanethiol) on acrylamide elimination were investigated in model systems. The obtained results showed that mercaptans assayed were effective in elimination arylamide in a model system. Their reactivities for decreasing acrylamide content depended on mercaptan's molecular structure...

An enzyme catalyzing the synthesis of L-cystathionine from the succinyl ester of L-homoserine and L-cysteine was isolated from a Salmonella mutant blocked in another step of methionine synthesis, and derepressed for cystathionine y-synthetase formation. The approximate molecular weight of the enzyme was 155,000 and it was unchanged after removal of tightly bound pyridoxal phosphate. In the abse...

Activated carbon has been used for many years for the adsorption of H2S and Mercaptans from natural gas streams, carbon dioxide, and sewage vents. It is widely thought that the carbon pore surface catalyses the oxidation of HzS to elemental sulfur and higher oxidized forms of su l fd2 . However, due to the poor loading capacities achieved at ambient conditions, most commercial activated carbon ...