A significantly high number of patients with anorexia nervosa are overweight immediately before the onset of the condition. This premorbid weight may be a feature of their constitution but is sometimes a more transitory phenomenon. Menstruation ceases early in the condition but usually within the context of significant weight loss. However, the subsequent amenorrhoea, related to factors that pr...

Polycystic ovary syndrome (PCOS) affects up to 15% of women of reproductive age and is characterized by hyperandrogenism, menstrual disturbance, anovulatory infertility and obesity. A large body of evidence has indicated that increased insulin resistance and compensatory hyperinsulinaemia play a key role in the pathogenesis of PCOS. At least 40% of women with PCOS are obese and are more insulin...

Norethisterone oenanthate (NET-OEN) was given as an injectable contraceptive to 295 healthy women over 1606 woman-months. A modified injection schedule was used. There were no pregnancies, and the 12-month, life-table, use-related discontinuation rate was 39.1/100 users. Menstrual disturbance (10.8/100 women), minor side effects (13.5/100 women), and personal reasons (12.0/100 women) were the m...

OBJECTIVE To analyse the progression of body mass index in eating disorders and to determine the percentile for establishment and resolution of the disease. METHODS A retrospective descriptive cross-sectional study. Review of clinical files of adolescents with eating disorders. RESULTS Of the 62 female adolescents studied with eating disorders, 51 presented with eating disorder not otherwis...

period despite maintaining a stable weight. The cause of these disturbances seemed to be located at or above the level of the hypothalamus in four patients and the pituitary in three, and one patient had polycystic ovaries. No patients suffering pituitary dysfunction had a history of anorexia nervosa. The ovarian ultrasound scan confirmed the test findings in all but one patient (case 11), in w...

BACKGROUND Conditions of low energy availability (EA) (<30 kcal/kgLBM) have been associated with suppressed metabolic hormones and reductions in LH pulsatility in previously sedentary women during short-term manipulations of energy intake (EI) and exercise energy expenditure (EEE) in a controlled laboratory setting. The purpose of this study was to examine if EA, defined as EA = (EI-EEE)/kgLBM,...

BACKGROUND Although the vaginal microflora (VMF) has been well studied, information on the fluctuation of the different bacterial species throughout the menstrual cycle and the information on events preceding the presence of disturbed VMF is still very limited. Documenting the dynamics of the VMF during the menstrual cycle might provide better insights. In this study, we assessed the presence o...

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. The clinical manifestation of PCOS varies from a mild menstrual disorder to severe disturbance of reproductive and metabolic functions. Management of women with PCOS depends on the symptoms. These could be ovulatory dysfunction-related infertility, menstrual disorders, or androgen-related symptoms. Weight loss impr...