The levonorgestrel-releasing intrauterine system (LNGIUS), Mirena®, has been licensed as a contraceptive in the UK since 1995. In 2002, Mirena became licensed also for the management of idiopathic menorrhagia and in 2004 the product licence was extended further to use for “endometrial protection” to prevent endometrial hyperplasia in women receiving oestrogen replacement therapy. We report a ca...

To study the effect of thermal balloon endometrial ablation in management of menorrhagia in high risk surgical candidates. The method is thirty patients with menorrhagia who were high risk candidates for surgery underwent uterine balloon therapy. Results were statistically analyzed regarding procedure, safety, side effects and prognostic factors at follow-up periods of one month, three months, ...

OBJECTIVES To determine whether uterine balloon therapy (UBT) for menorrhagia can be performed safely in the community setting, obviating the need for hospital admission or general anaesthesia. DESIGN Prospective case studies of 20 women undergoing Thermachoice endometrial ablation for menorrhagia. SETTING Glasgow Centre for Family Planning and Reproductive Health Care, Greater Glasgow Prim...

A prospective study of the management of menorrhagia in new patients presenting to gynaecological outpatients was undertaken at four centres in Northern Ireland and two in Great Britain. 325 patients were enrolled, the majority of whom (87%) had severe menorrhagia. Patients in all six centres were similar in relation to age, marital status, parity, use of contraception and severity of symptoms....

INTRODUCTION To make chiropractors more aware of menorrhagia and how they can serve a role in their patient's care and education since women make up 60% of the population seeking chiropractic care. METHOD A review of the biomedical literature on menorrhagia was conducted. Items that were retrieved were synthesized and interpreted in order to give the best information to practicing chiropracto...

Menorrhagia is the most common symptom that is experienced by women with bleeding disorders. Von Willebrand disease (VWD) is the most common congenital human bleeding disorder that is manifested as a quantitative deficiency in Von Willebrand factor (VWF) or dysfunction of this factor. The frequency of VWD is similar in both men and women. However, VWD is more readily detected in women due to th...

Aquaporin-1 (AQP1) is a water channel protein expressed in vascular endothelia and involved in impaired angiogenesis in tumors. Since angiogenesis is an essential component of the regeneration of the endometrium, we sought to analyze the expression of AQP1 in endometrial blood vessels in normal cyclic endometrium as well as in endometrial biopsies of menorrhagia patients. Endometrial biopsies f...