In a prospective follow-up of memory functions after head injury, 61 patients were tested with P.G.I. Memory Scale at the end of 18 months. Patients with acceleration injuries showed a poor performance in comparison to those with contact injuries. Memory was found to be related to indices of severity of injury, particularly post traumatic amnesia (PTA). Presence of fracture of skull or early ne...

Posttraumatic stress disorder (PTSD) is a disorder of emotional and mental stress occurring as an outcome of injury or severe emotional shock. Several Neuroimaging studies in humans have shown the functions and relationship between the anatomical changes of brain and PTSD. The three major areas of the brain are affected by PTSD .These three areas are the amygdala, hippocampus and prefrontal cor...

Traumatic brain injury (TBI) may have a profound impact on a child's ongoing development. Various risk factors have been found to predict outcome, but considerable variability remains unexplained. This study used a prospective, longitudinal design to examine recovery of memory function following TBI within the pre-school period. Forty-four children with TBI were divided according to injury seve...

objective: stroke is most important cause of death and disability in adults. the hippocampal ca1 and sub-ventricular zone neurons are vulnerable to ischemia that can impair memory and learning functions. although neurogenesis normally occurs in the dentate gyrus (dg) of the hippocampus and sub-ventricular zone (svz) following brain damage, this response is unable to compensate for severely dama...

Memory deficits are among the most frequently reported sequelae of mild traumatic brain injury (MTBI), especially early after injury. To date, these cognitive deficits remain poorly understood, as in most patients the brain is macroscopically intact. To identify the mechanism by which MTBI causes declarative memory impairments, we probed the functionality of the medial temporal lobe (MTL) and t...

posttraumatic stress disorder (ptsd) is a disorder of emotional and mental stress occurring as an outcome of injury or severe emotional shock. several neuroimaging studies in humans have shown the functions and relationship between the anatomical changes of brain and ptsd. the three major areas of the brain are affected by ptsd .these three areas are the amygdala, hippocampus and prefrontal cor...

Background: The paced auditory serial addition test (PASAT) was primarily developed to assess the effects of traumatic brain injury on cognitive functioning. Working memory (WM) is one of the most important aspects of cognitive function, and WM impairment is one of the clinically remarkable signs of aphasia. To develop the Persian version of PASAT, an initial version was used in individuals wit...

objective(s):global cerebral ischemia-reperfusion injury causes loss of pyramidal cells in ca1 region of hippocampus. in this study, we investigated the possible neuroprotective effects of the ethanol extract of cyperus rotundus (eecr) on a model of global transient ischemia in rat, by evaluating the pathophysiology of the hippocampal tissue and spatial memory. materials and methods: treatment ...

Eighty-two patients with severe head injury were tested on the Wechsler Memory Scale and compared with 34 normal subjects. Head injured patients had severe memory difficulties, particularly on Logical Memory and Associate Learning. Severity of head injury (post-traumatic amnesia duration) was related to poor memory, as was increasing age, but both persisting neurological signs, including dyspha...